anti-CD24 antibody [30-F1] (PE)
CAT.NO. : ARG22089
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概述
| 产品描述 | PE-conjugated Rat Monoclonal antibody [30-F1] recognizes CD24 |
|---|---|
| 反应物种 | Ms |
| 应用 | FACS |
| 特异性 | Mouse CD24 |
| 宿主 | Rat |
| 克隆 | Monoclonal |
| 克隆号 | 30-F1 |
| 同位型 | IgG2c, kappa |
| 靶点名称 | CD24 |
| 抗原物种 | Mouse |
| 抗原 | Mouse thymus or spleen |
| 偶联标记 | PE |
| 別名 | Signal transducer CD24; CD antigen CD24; CD24A; Small cell lung carcinoma cluster 4 antigen |
应用说明
| 应用建议 |
| ||||
|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 缓冲液 | PBS, 0.1% Sodium azide and Sucrose. |
| 抗菌剂 | 0.1% Sodium azide |
| 稳定剂 | Sucrose |
| 浓度 | 0.1 mg/ml |
| 存放说明 | Aliquot and store in the dark at 2-8°C. Keep protected from prolonged exposure to light. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 基因名称 | CD24 |
|---|---|
| 全名 | CD24a antigen |
| 背景介绍 | This gene encodes a sialoglycoprotein that is expressed on mature granulocytes and B cells and modulates growth and differentiation signals to these cells. The precursor protein is cleaved to a short 32 amino acid mature peptide which is anchored via a glycosyl phosphatidylinositol (GPI) link to the cell surface. This gene was missing from previous genome assemblies, but is properly located on chromosome 6. Non-transcribed pseudogenes have been designated on chromosomes 1, 15, 20, and Y. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2014] |
| 生物功能 | Modulates B-cell activation responses. Signaling could be triggered by the binding of a lectin-like ligand to the CD24 carbohydrates, and transduced by the release of second messengers derived from the GPI-anchor. Promotes AG-dependent proliferation of B-cells, and prevents their terminal differentiation into antibody-forming cells. [UniProt] |
| 预测分子量 | 8 kDa |
| 翻译后修饰 | Extensively O-glycosylated. |
检测图片 (2)
ARG22089 anti-CD24 antibody [30-F1] (PE) FACS image
Flow Cytometry: BALB/c Mouse splenocytes stained with ARG22089 anti-CD24 antibody [30-F1] (PE).
ARG22089 anti-CD24 antibody [30-F1] (PE) FACS image
Flow Cytometry: BALB/c Mouse splenocytes stained with ARG22089 anti-CD24 antibody [30-F1] (PE) and ARG20850 anti-CD19 antibody [6D5] (FITC).
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