anti-CD25 antibody [IL2R.1]

Key features and details

  • 产品描述: Mouse Monoclonal antibody [IL2R.1] recognizes CD25
  • 反应物种: Hu
  • 应用: FACS, IHC-Fr, IHC-P
  • 特异性: Specific to a 55 kDa protein known as interleukin 2-receptor (IL-2R alpha). IL-2R alpha is over expressed on the surface of activated T cell, HTLV-1 or HTLV-2 positive T cell lines and moderately expressed on activated B cells, NK-cells and macrophages.
  • 宿主: Mouse
  • 克隆: Monoclonal
  • 克隆号: IL2R.1
  • 同位型: IgG1
  • 靶点名称: CD25
  • Brand:
CAT.NO. : ARG62407
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Product Details
概述
产品描述Mouse Monoclonal antibody [IL2R.1] recognizes CD25
反应物种Hu
应用FACS, IHC-Fr, IHC-P
特异性Specific to a 55 kDa protein known as interleukin 2-receptor (IL-2R alpha). IL-2R alpha is over expressed on the surface of activated T cell, HTLV-1 or HTLV-2 positive T cell lines and moderately expressed on activated B cells, NK-cells and macrophages.
宿主Mouse
克隆Monoclonal
克隆号IL2R.1
同位型IgG1
靶点名称CD25
抗原物种Human
抗原BALB/C mice were injected with recombinant human interleukin-2 receptor
偶联标记Un-conjugated
別名IL-2-RA; IL-2 receptor subunit alpha; CD25; TCGFR; TAC antigen; IL2R; CD antigen CD25; Interleukin-2 receptor subunit alpha; IL-2R subunit alpha; p55; IL2-RA; IDDM10
应用说明
应用说明FACS: 1/50.
IHC-P: 1/20 - 1/50.
* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
阳性对照Tonsil
属性
形式Liquid
纯化Protein A purified
缓冲液PBS (pH 7.2), 0.2% BSA and 0.09% Sodium azide
抗菌剂0.09% Sodium azide
稳定剂0.2% BSA
浓度0.2 mg/ml
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
数据库连接

GeneID: 3559 Human IL2RA

Swiss-port # P01589 Human Interleukin-2 receptor subunit alpha

基因名称IL2RA
全名interleukin 2 receptor, alpha
背景介绍The interleukin 2 (IL2) receptor alpha (IL2RA) and beta (IL2RB) chains, together with the common gamma chain (IL2RG), constitute the high-affinity IL2 receptor. Homodimeric alpha chains (IL2RA) result in low-affinity receptor, while homodimeric beta (IL2RB) chains produce a medium-affinity receptor. Normally an integral-membrane protein, soluble IL2RA has been isolated and determined to result from extracellular proteolyisis. Alternately-spliced IL2RA mRNAs have been isolated, but the significance of each is presently unknown. Mutations in this gene are associated with interleukin 2 receptor alpha deficiency.[provided by RefSeq, Nov 2009]
生物功能Receptor for interleukin-2. [UniProt]
细胞定位Membrane.
研究领域Immune System antibody; Pre-B Cell Marker antibody
预测分子量31 kDa
参考文献

克隆号文献

CD25 is a novel marker of hepatic bile canaliculus.

IHC / Human

Lu ZH et al.
Int J Surg Pathol.,  (2012)

publication_link

 

hr_line

FOXP3 T regulatory cells in lesions of oral lichen planus correlated with disease activity.

IHC / Human

Tao XA et al.
Oral Dis.,  (2010)

publication_link

 

hr_line

Regulatory T cells and liver pathology in a murine graft versus host response model.

IHC / Mouse

Miyazaki T et al.
Hepatol Res.,  (2009)

publication_link

 

hr_line

Pathway analysis of coronary atherosclerosis.

IHC-Fr / Human

King JY et al.
Physiol Genomics.,  (2005)

publication_link

 

hr_line

Focal complex formation in adult cardiomyocytes is accompanied by the activation of beta3 integrin and c-Src.

WB / Human

Willey CD et al.
J Mol Cell Cardiol.,  (2003)

publication_link

 

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