anti-CD25 antibody [KEI-alpha1]

Key features and details

  • 产品描述: Mouse Monoclonal antibody [KEI-alpha1] recognizes CD25This antibody recognizes Rabbit CD5, a 55kDa cell surface antigen, otherwise known as the interleukin-2 (IL-2) receptor alpha chain. In Rabbits, CD25 is expressed on activated T lymphocytes.Mouse anti Rabbit CD25 antibody, clone KEI-alpha1 is reported to inhibit the binding of IL-2 to its receptor (Kotani et al. 1993).
  • 反应物种: Rb
  • 不反应物种: Hu
  • 应用: FACS, IHC-Fr, IP
  • 宿主: Mouse
  • 克隆: Monoclonal
  • 克隆号: KEI-alpha1
  • 同位型: IgG2b
  • 靶点名称: CD25
  • Brand:
CAT.NO. : ARG22714
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Product Details
概述
产品描述Mouse Monoclonal antibody [KEI-alpha1] recognizes CD25
This antibody recognizes Rabbit CD5, a 55kDa cell surface antigen, otherwise known as the interleukin-2 (IL-2) receptor alpha chain. In Rabbits, CD25 is expressed on activated T lymphocytes.
Mouse anti Rabbit CD25 antibody, clone KEI-alpha1 is reported to inhibit the binding of IL-2 to its receptor (Kotani et al. 1993).
反应物种Rb
不反应物种Hu
应用FACS, IHC-Fr, IP
宿主Mouse
克隆Monoclonal
克隆号KEI-alpha1
同位型IgG2b
靶点名称CD25
抗原物种Rabbit
抗原Cell membrane preparation of HTLV-1 transformed rabbit T cell line.
偶联标记Un-conjugated
別名IL-2-RA; IL-2 receptor subunit alpha; CD25; TCGFR; TAC antigen; IL2R; CD antigen CD25; Interleukin-2 receptor subunit alpha; IL-2R subunit alpha; p55; IL2-RA; IDDM10
应用说明
应用建议
应用推荐稀释比
FACS1:100 - 1:200
IHC-FrAssay-dependent
IPAssay-dependent
应用说明FACS: Use 10 µl of the suggested working dilution to label 10^6 cells in 100 µl.
* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
属性
形式Liquid
纯化Purification with Protein G.
缓冲液PBS and 0.09% Sodium azide.
抗菌剂0.09% Sodium azide
浓度1 mg/ml
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
基因名称IL2RA
全名interleukin 2 receptor, alpha
背景介绍The interleukin 2 (IL2) receptor alpha (IL2RA) and beta (IL2RB) chains, together with the common gamma chain (IL2RG), constitute the high-affinity IL2 receptor. Homodimeric alpha chains (IL2RA) result in low-affinity receptor, while homodimeric beta (IL2RB) chains produce a medium-affinity receptor. Normally an integral-membrane protein, soluble IL2RA has been isolated and determined to result from extracellular proteolyisis. Alternately-spliced IL2RA mRNAs have been isolated, but the significance of each is presently unknown. Mutations in this gene are associated with interleukin 2 receptor alpha deficiency.[provided by RefSeq, Nov 2009]
生物功能Receptor for interleukin-2. [UniProt]
研究领域Immune System antibody; Pre-B Cell Marker antibody
预测分子量31 kDa
检测图片 (1)
  • ARG22714 anti-CD25 antibody [KEI-alpha1] FACS image

    Flow Cytometry: Rabbit peripheral blood lymphocytes stained with ARG22714 anti-CD25 antibody [KEI-alpha1] followed by Goat anti-Mouse IgG (FITC).

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