anti-CD25 antibody [SQab20197]

Key features and details

  • 产品描述: Recombinant Rabbit Monoclonal antibody [SQab20197] recognizes CD25
  • 反应物种: Hu
  • 应用: IHC-P
  • 宿主: Rabbit
  • 克隆: Monoclonal
  • 克隆号: SQab20197
  • 同位型: IgG
  • 靶点名称: CD25
  • 抗原物种: Human
  • Brand:
CAT.NO. : ARG66764
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Product Details
概述
产品描述Recombinant Rabbit Monoclonal antibody [SQab20197] recognizes CD25
反应物种Hu
应用IHC-P
宿主Rabbit
克隆Monoclonal
克隆号SQab20197
同位型IgG
靶点名称CD25
抗原物种Human
抗原Recombinant fragment within aa. 1-250 of Human CD25.
偶联标记Un-conjugated
別名IL-2-RA; IL-2 receptor subunit alpha; CD25; TCGFR; TAC antigen; IL2R; CD antigen CD25; Interleukin-2 receptor subunit alpha; IL-2R subunit alpha; p55; IL2-RA; IDDM10
应用说明
应用建议
应用推荐稀释比
IHC-P1:100 - 1:200
应用说明IHC-P: Antigen Retrieval: Heat mediation was performed in Tris/EDTA buffer (pH 9.0).
* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
阳性对照Colon carcinoma tissue.
属性
形式Liquid
纯化Purification with Protein A.
缓冲液PBS, 0.01% Sodium azide, 40% Glycerol and 0.05% BSA.
抗菌剂0.01% Sodium azide
稳定剂40% Glycerol and 0.05% BSA
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
数据库连接

GeneID: 3559 Human IL2RA

Swiss-port # P01589 Human Interleukin-2 receptor subunit alpha

基因名称IL2RA
全名interleukin 2 receptor, alpha
背景介绍The interleukin 2 (IL2) receptor alpha (IL2RA) and beta (IL2RB) chains, together with the common gamma chain (IL2RG), constitute the high-affinity IL2 receptor. Homodimeric alpha chains (IL2RA) result in low-affinity receptor, while homodimeric beta (IL2RB) chains produce a medium-affinity receptor. Normally an integral-membrane protein, soluble IL2RA has been isolated and determined to result from extracellular proteolyisis. Alternately-spliced IL2RA mRNAs have been isolated, but the significance of each is presently unknown. Mutations in this gene are associated with interleukin 2 receptor alpha deficiency. [provided by RefSeq, Nov 2009]
生物功能Receptor for interleukin-2. The receptor is involved in the regulation of immune tolerance by controlling regulatory T cells (TREGs) activity. TREGs suppress the activation and expansion of autoreactive T-cells. [UniProt]
细胞定位Membrane; Single-pass type I membrane protein. [UniProt]
预测分子量31 kDa
检测图片 (1)
  • ARG66764 anti-CD25 antibody [SQab20197] IHC-P image

    Immunohistochemistry: Formalin/PFA-fixed and paraffin-embedded Human colon carcinoma tissue. Antigen Retrieval: Heat mediation was performed in Tris/EDTA buffer (pH 9.0). The tissue section was stained with ARG66764 anti-CD25 antibody [SQab20197] at 18°C - 25°C for 30 minutes.

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