anti-CD273 / PD-L2 antibody [24F.10C12]
![anti-CD273 / PD-L2 antibody [24F.10C12]](/upload/image/20241105/8415bc38bc270b898ee2a90369a6c7fb.jpg)
Key features and details
- 产品描述:
- 反应物种:
- 应用:
- 特异性:
- 宿主:
- 克隆:
- 克隆号:
- 同位型:
- 靶点名称:
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Brand:
CAT.NO. : ARG66227
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Product Details
概述
| 产品描述 | Mouse Monoclonal antibody [24F.10C12] recognizes CD273 / PD-L2 |
|---|---|
| 反应物种 | Hu |
| 应用 | CyTOF®-candidate, FACS, FuncSt, IHC-Fr |
| 特异性 | This antibody recognizes CD273 / PD-L2 (also known as B7-DC), a 25 kDa type I transmembrane protein expressed by dendritic cells, activated monocytes and T cells, heart, first trimester placenta, lung and liver, as well as in Hodgkin's lymphoma cells and primary mediastinal B cell lymphoma (PMBL). |
| 宿主 | Mouse |
| 克隆 | Monoclonal |
| 克隆号 | 24F.10C12 |
| 同位型 | IgG2a |
| 靶点名称 | CD273 / PD-L2 |
| 抗原物种 | Human |
| 抗原 | Human CD273. |
| 偶联标记 | Un-conjugated |
| 別名 | B7DC; bA574F11.2; PDL2; CD antigen CD273; PD-L2; Programmed cell death 1 ligand 2; CD273; Btdc; PDCD1L2; Programmed death ligand 2; Butyrophilin B7-DC; B7-DC; PD-1 ligand 2; PDCD1 ligand 2 |
应用说明
| 应用建议 |
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|---|---|---|---|---|---|---|---|---|---|---|---|
| 应用说明 | Functional study: anti-CD273 / PD-L2 antibody [24F.10C12] can be used to block PD-1 binding to its ligand. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purification with Protein A. |
| 纯度 | > 95% (by SDS-PAGE) |
| 缓冲液 | PBS (pH 7.4) and 15 mM Sodium azide. |
| 抗菌剂 | 15 mM Sodium azide |
| 浓度 | 1 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | PDCD1LG2 |
| 全名 | programmed cell death 1 ligand 2 |
| 生物功能 | Involved in the costimulatory signal, essential for T-cell proliferation and IFNG production in a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production (By similarity). [UniProt] |
| 产品亮点 | Related products: PD-L2 antibodies; PD-L2 ELISA Kits; Anti-Mouse IgG secondary antibodies; Related news: CyTOF-candidate Antibodies The best solution for PD-1/PD-L1 research |
| 预测分子量 | 31 kDa |
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