anti-CD273 / PD-L2 antibody [24F.10C12] (PE)

产品描述: PE-conjugated Mouse Monoclonal antibody [24F.10C12] recognizes CD273 / PD-L2
反应物种: Hu
应用: FACS
特异性: The mouse monoclonal antibody 24F.10C12 recognizes an extracellular epitope of CD273 / PD-L2 (also known as B7-DC), a 25 kDa type I transmembrane protein expressed by dendritic cells, activated monocytes and T cells, heart, first trimester placenta, lung and liver, as well as in Hodgkin´s lymphoma cells and primary mediastinal B cell lymphoma (PMBL).
宿主: Mouse
克隆: Monoclonal
克隆号: 24F.10C12
同位型: IgG2a, kappa
靶点名称: CD273 / PD-L2

CAT.NO. : ARG42339

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Size:

50 tests

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Product Details

概述

产品描述	PE-conjugated Mouse Monoclonal antibody [24F.10C12] recognizes CD273 / PD-L2
反应物种	Hu
应用	FACS
特异性	The mouse monoclonal antibody 24F.10C12 recognizes an extracellular epitope of CD273 / PD-L2 (also known as B7-DC), a 25 kDa type I transmembrane protein expressed by dendritic cells, activated monocytes and T cells, heart, first trimester placenta, lung and liver, as well as in Hodgkin´s lymphoma cells and primary mediastinal B cell lymphoma (PMBL).
宿主	Mouse
克隆	Monoclonal
克隆号	24F.10C12
同位型	IgG2a, kappa
靶点名称	CD273 / PD-L2
抗原物种	Human
抗原	Human CD273.
偶联标记	PE
別名	B7DC; bA574F11.2; PDL2; CD antigen CD273; PD-L2; Programmed cell death 1 ligand 2; CD273; Btdc; PDCD1L2; Programmed death ligand 2; Butyrophilin B7-DC; B7-DC; PD-1 ligand 2; PDCD1 ligand 2

应用说明

应用建议

应用	推荐稀释比
FACS	10 µl / 100 µl of whole blood or 10^6 cells

应用说明

* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

属性

形式	Liquid
纯化	Purified
缓冲液	PBS and 15 mM Sodium azide.
抗菌剂	15 mM Sodium azide
存放说明	Aliquot and store in the dark at 2-8°C. Keep protected from prolonged exposure to light. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项	For laboratory research only, not for drug, diagnostic or other use.

生物信息

数据库连接	GeneID: 80380 Human PDCD1LG2 Swiss-port # Q9BQ51 Human Programmed cell death 1 ligand 2
基因名称	PDCD1LG2
全名	programmed cell death 1 ligand 2
生物功能	Involved in the costimulatory signal, essential for T-cell proliferation and IFNG production in a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production (By similarity). [UniProt]
细胞定位	Isoform 3: Secreted. Isoform 2: Endomembrane system; Single-pass type I membrane protein. Isoform 1: Cell membrane; Single-pass type I membrane protein. [UniProt]
预测分子量	31 kDa

检测图片 (3)

ARG42339 anti-CD273 / PD-L2 antibody [24F.10C12] (PE) FACS image
Flow Cytometry: Human GM-CSF and IL-4 stimulated peripheral blood mononuclear cells stained with ARG42339 anti-CD273 / PD-L2 antibody [24F.10C12] (PE) at 10 µl / 10^6 cells in 100 µl of cell suspension.
ARG42339 anti-CD273 / PD-L2 antibody [24F.10C12] (PE) FACS image
Flow Cytometry: Human GM-CSF and IL-4 stimulated peripheral blood mononuclear cells stained with ARG42339 anti-CD273 / PD-L2 antibody [24F.10C12] (PE) at 10 µl / 10^6 cells in 100 µl of cell suspension and ARG53761 anti-CD11c antibody [BU15] (APC) at 10 µl / 100 µl of peripheral whole blood.
ARG42339 anti-CD273 / PD-L2 antibody [24F.10C12] (PE) FACS image
Flow Cytometry: Separation of Human CD273 positive CD11c positive cells (red-filled) from CD273 negative CD11c negative cells (black-dashed). Human GM-CSF and IL-4 stimulated peripheral blood mononuclear cells stained with ARG42339 anti-CD273 / PD-L2 antibody [24F.10C12] (PE) at 10 µl / 10^6 cells in 100 µl of cell suspension.

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