anti-CD300e antibody [UP-H2] (APC)
![anti-CD300e antibody [UP-H2] (APC)](/upload/image/products/ARG54303_FACS_1_210_205.jpg)
![anti-CD300e antibody [UP-H2] (APC)](/upload/image/products/ARG54303_FACS_1.jpg)
Key features and details
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CAT.NO. : ARG54303
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Product Details
概述
| 产品描述 | APC-conjugated Mouse Monoclonal antibody [UP-H2] recognizes CD300e |
|---|---|
| 反应物种 | Hu |
| 应用 | FACS |
| 特异性 | The clone UP-H2 recognizes CD300e / IREM-2, a 32 kDa glycoprotein expressed by mature monocytes and peripheral blood myeloid dendritic cells. |
| 宿主 | Mouse |
| 克隆 | Monoclonal |
| 克隆号 | UP-H2 |
| 同位型 | IgG1 |
| 靶点名称 | CD300e |
| 抗原 | CD300e-HA-transfected cells |
| 偶联标记 | APC |
| 別名 | Poly-Ig receptor 2; Immune receptor expressed on myeloid cells 2; IREM-2; CD300LE; CMRF35-A5; CD antigen CD300e; CLM2; IREM2; CMRF35-like molecule 2; PIgR2; CLM-2; Polymeric immunoglobulin receptor 2; PIgR-2; CD300 antigen-like family member E |
应用说明
| 应用建议 |
| ||||
|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化说明 | The purified antibody is conjugated with cross-linked Allophycocyanin (APC) under optimum conditions. The conjugate is purified by size-exclusion chromatography and adjusted for direct use. No reconstitution is necessary. |
| 缓冲液 | PBS, 15 mM Sodium azide and 0.2% (w/v) high-grade protease free BSA |
| 抗菌剂 | 15 mM Sodium azide |
| 稳定剂 | 0.2% (w/v) high-grade protease free BSA |
| 存放说明 | Aliquot and store in the dark at 2-8°C. Keep protected from prolonged exposure to light. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | CD300E |
| 全名 | CD300e molecule |
| 背景介绍 | CD300e / IREM-2 (immune receptor expressed by myeloid cells 2), also known as CLM2 or LMIR6, is a monomeric transmembrane glycoprotein with a single extracellular immunoglobulin-like domain. Intracellularly it associates with DAP-12, an ITAM-containing adaptor molecule. CD300e is expressed on mature monocytes and peripheral blood myeloid dendritic cells. Its crosslinking leads to release of pro-inflammatory cytokines, and increased expression of activation markers. |
| 生物功能 | Probably acts as an activating receptor. [UniProt] |
| 研究领域 | Immune System antibody |
| 预测分子量 | 23 kDa |
| 翻译后修饰 | N-glycosylated. |
检测图片 (1)
ARG54303 anti-CD300e antibody [UP-H2] (APC) FACS image
Flow Cytometry: Human peripheral blood stained with ARG54303 anti-CD300e antibody [UP-H2] (APC).
参考文献
克隆号文献
Molecular characterization of a novel immune receptor restricted to the monocytic lineage.
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