anti-CD321 / JAM1 antibody

Key features and details

  • 产品描述: Rabbit polyclonal antibody recognizes CD321 / JAM1.
  • 反应物种: Hu
  • 应用: FACS, ICC/IF, IHC-P, WB
  • 宿主: Rabbit
  • 克隆: Polyclonal
  • 同位型: IgG
  • 靶点名称: CD321 / JAM1
  • 抗原物种: Human
  • 抗原: Human JAM-A/F11R recombinant protein (a.a: S28-T294).
  • Brand:
CAT.NO. : ARG45056
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Product Details
概述
产品描述Rabbit polyclonal antibody recognizes CD321 / JAM1.
反应物种Hu
应用FACS, ICC/IF, IHC-P, WB
宿主Rabbit
克隆Polyclonal
同位型IgG
靶点名称CD321 / JAM1
抗原物种Human
抗原Human JAM-A/F11R recombinant protein (a.a: S28-T294).
偶联标记Un-conjugated
別名F11R; F11 Receptor; PAM-1; JCAM; Junctional Adhesion Molecule 1; JAM-1; JAM-A; CD321; JAMA; JAM1; Junctional Adhesion Molecule A; Platelet Adhesion Molecule 1; Platelet F11 Receptor; CD321 Antigen; JAM; KAT
应用说明
应用建议
应用推荐稀释比
FACS1 - 3 μg / 1x10^6 cells
ICC/IF5 μg / ml
IHC-P2 - 5 μg / ml
WB0.25 - 0.5 μg / ml
应用说明* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
属性
形式Liquid
缓冲液0.9% NaCl, 0.2% Na2HPO4 and 4% Trehalose.
稳定剂4% Trehalose
浓度0.5 mg/ml
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
数据库连接

GeneID: 50848 Human F11R

Swiss-port # Q9Y624 Human Junctional adhesion molecule A

基因名称F11R
全名F11 receptor
背景介绍Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. The protein encoded by this immunoglobulin superfamily gene member is an important regulator of tight junction assembly in epithelia. In addition, the encoded protein can act as (1) a receptor for reovirus, (2) a ligand for the integrin LFA1, involved in leukocyte transmigration, and (3) a platelet receptor. Multiple 5' alternatively spliced variants, encoding the same protein, have been identified but their biological validity has not been established. [provided by RefSeq, Jul 2008]
生物功能Plays a role in regulating monocyte transmigration involved in integrity of epithelial barrier. Involved in platelet activation. In case of orthoreovirus infection, serves as receptor for the virus. [UniProt]
预测分子量33 kDa
翻译后修饰Disulfide bond, Glycoprotein, Phosphoprotein. [UniProt]
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