anti-CD34 antibody [Q19-E]

Key features and details

  • 产品描述: Rabbit Monoclonal antibody [Q19-E] recognizes CD34
  • 反应物种: Hu
  • 应用: IHC-P
  • 宿主: Rabbit
  • 克隆: Monoclonal
  • 克隆号: Q19-E
  • 同位型: IgG
  • 靶点名称: CD34
  • 抗原物种: Human
  • Brand:
CAT.NO. : ARG10557
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Product Details
概述
产品描述Rabbit Monoclonal antibody [Q19-E] recognizes CD34
反应物种Hu
应用IHC-P
宿主Rabbit
克隆Monoclonal
克隆号Q19-E
同位型IgG
靶点名称CD34
抗原物种Human
抗原Synthetic peptide around the N-terminus of Human CD34
偶联标记Un-conjugated
別名Hematopoietic progenitor cell antigen CD34; CD antigen CD34
应用说明
应用建议
应用推荐稀释比
IHC-P1:100 - 1:200
应用说明* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
属性
形式Liquid
缓冲液20 mM Tris-HCl (pH 8.0), 0.05% Sodium azide and 20 mg/ml BSA
抗菌剂0.05% Sodium azide
稳定剂20 mg/ml BSA
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
数据库连接

GeneID: 947 Human CD34

Swiss-port # P28906 Human Hematopoietic progenitor cell antigen CD34

基因名称CD34
全名CD34 molecule
背景介绍CD34 protein may play a role in the attachment of stem cells to the bone marrow extracellular matrix or to stromal cells. This single-pass membrane protein is highly glycosylated and phosphorylated by protein kinase C. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011]
生物功能CD34 is a possible adhesion molecule with a role in early hematopoiesis by mediating the attachment of stem cells to the bone marrow extracellular matrix or directly to stromal cells. Could act as a scaffold for the attachment of lineage specific glycans, allowing stem cells to bind to lectins expressed by stromal cells or other marrow components. Presents carbohydrate ligands to selectins. [UniProt]
研究领域Cancer antibody; Cell Biology and Cellular Response antibody; Controls and Markers antibody; Developmental Biology antibody; Immune System antibody; Neuroscience antibody; Pro-B Cell Marker antibody; Endothelial Cell Marker antibody; Angiogenesis Study antibody
预测分子量41 kDa
翻译后修饰Highly glycosylated.
Phosphorylated on serine residues by PKC.
检测图片 (2)
  • ARG10557 anti-CD34 antibody [Q19-E] IHC-P image

    Immunohistochemistry: Formalin fixed, paraffin embedded Human GIST (gastrointestinal stromal tumor) of small intestine (4 µm sections) stained with ARG10557 anti-CD34 antibody [Q19-E].

  • ARG10557 anti-CD34 antibody [Q19-E] IHC-P image

    Immunohistochemistry: Formalin fixed, paraffin embedded Human endothelium of the muscular artery (4 µm sections) stained with ARG10557 anti-CD34 antibody [Q19-E].

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