anti-CD37 antibody [MB-1] (FITC)
CAT.NO. : ARG44611
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概述
| 产品描述 | FITC-conjugated Mouse Monoclonal antibody recognizes CD37 |
|---|---|
| 反应物种 | Hu |
| 应用 | FACS |
| 宿主 | Mouse |
| 克隆 | Monoclonal |
| 克隆号 | MB-1 |
| 同位型 | IgG1 kappa |
| 靶点名称 | CD37 |
| 抗原物种 | Human |
| 偶联标记 | FITC |
| 別名 | CD37; CD37 Molecule; TSPAN26; Leukocyte Antigen CD37; Tetraspanin-26; CD37 Antigen; Tspan-26; Cell Differentiation Antigen 37; Leukocyte Surface Antigen CD37; GP52-40 |
应用说明
| 应用建议 |
| ||||
|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purified antibody is conjugated with fluorescein isothiocyanate (FITC), and unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography. |
| 缓冲液 | PBS (pH 7.4) and 15 mM Sodium azide |
| 抗菌剂 | 15 mM Sodium azide |
| 存放说明 | Aliquot and store in the dark at 2-8°C. Keep protected from prolonged exposure to light. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | CD37 |
| 全名 | CD37 Molecule |
| 背景介绍 | The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins and other transmembrane 4 superfamily proteins. It may play a role in T-cell-B-cell interactions. Alternate splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008] |
| 生物功能 | Alternatively, inhibition of IL-6 signaling can also occur via interaction and stabilization of DECTIN1/CLEC7A at the cell membrane to inhibit its ability to promote the production of IL-6. [UniProt] |
| 细胞定位 | Cell membrane, Membrane. [UniProt] |
| 预测分子量 | 32 kDa |
| 翻译后修饰 | Glycoprotein. [UniProt] |
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