anti-CD49b / Integrin alpha 2 antibody [DX5] (APC)

产品描述: APC-conjugated Rat Monoclonal antibody [DX5] recognizes CD49b / Integrin alpha 2
反应物种: Ms
应用: FACS, IHC-Fr, IHC-P
特异性: The clone DX5 reacts with CD49b, also known as very late antigen-2 (VLA-2) and α2 integrin. The antibody stains the majority of NK cells and a small subpopulation of T cells in all mouse strains tested (e.g., A/J, AKR, BALB/c, C3H/HeJ, C57BL/6, C57BL/10, C57BR, C58, CBA/Ca, CBA/J, DBA/1, DBA/2, SJL, SWR). The clone DX5 has not been demonstrated to have activating or blocking activity.
宿主: Rat
克隆: Monoclonal
克隆号: DX5
同位型: IgM, kappa
靶点名称: CD49b / Integrin alpha 2

CAT.NO. : ARG21030

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Size:

50 μg

*产品价格可能会有所调整，请以品牌方官网实时更新的价格为准，以确保准确性。

Product Details

概述

产品描述	APC-conjugated Rat Monoclonal antibody [DX5] recognizes CD49b / Integrin alpha 2
反应物种	Ms
应用	FACS, IHC-Fr, IHC-P
特异性	The clone DX5 reacts with CD49b, also known as very late antigen-2 (VLA-2) and α2 integrin. The antibody stains the majority of NK cells and a small subpopulation of T cells in all mouse strains tested (e.g., A/J, AKR, BALB/c, C3H/HeJ, C57BL/6, C57BL/10, C57BR, C58, CBA/Ca, CBA/J, DBA/1, DBA/2, SJL, SWR). The clone DX5 has not been demonstrated to have activating or blocking activity.
宿主	Rat
克隆	Monoclonal
克隆号	DX5
同位型	IgM, kappa
靶点名称	CD49b / Integrin alpha 2
抗原物种	Mouse
抗原	NK cells isolated from C57BL/6 mice
偶联标记	APC
別名	Collagen receptor; VLA-2 subunit alpha; HPA-5; CD49B; CD49 antigen-like family member B; GPIa; VLA-2; CD antigen CD49b; BR; VLAA2; Platelet membrane glycoprotein Ia; Integrin alpha-2

应用说明

应用建议

应用说明

* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

属性

形式	Liquid
缓冲液	PBS, 0.1% Sodium azide and Sucrose.
抗菌剂	0.1% Sodium azide
稳定剂	Sucrose
浓度	0.1 mg/ml
存放说明	Aliquot and store in the dark at 2-8°C. Keep protected from prolonged exposure to light. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项	For laboratory research only, not for drug, diagnostic or other use.

生物信息

数据库连接	GeneID: 16398 Mouse ITGA2 Swiss-port # Q62469 Mouse Integrin alpha-2
基因名称	ITGA2
全名	integrin alpha 2
背景介绍	This gene encodes the alpha subunit of a transmembrane receptor for collagens and related proteins. The encoded protein forms a heterodimer with a beta subunit and mediates the adhesion of platelets and other cell types to the extracellular matrix. Loss of the encoded protein is associated with bleeding disorder platelet-type 9. Antibodies against this protein are found in several immune disorders, including neonatal alloimmune thrombocytopenia. This gene is located adjacent to a related alpha subunit gene. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012]
生物功能	Integrin alpha-2/beta-1 is a receptor for laminin, collagen, collagen C-propeptides, fibronectin and E-cadherin. It recognizes the proline-hydroxylated sequence G-F-P-G-E-R in collagen. It is responsible for adhesion of platelets and other cells to collagens, modulation of collagen and collagenase gene expression, force generation and organization of newly synthesized extracellular matrix. [UniProt]
预测分子量	129 kDa

检测图片 (1)

ARG21030 anti-CD49b / Integrin alpha 2 antibody [DX5] (APC) FACS image
Flow Cytometry: C57BL/6 Mouse splenocytes stained with ARG21030 anti-CD49b / Integrin alpha 2 antibody [DX5] (APC) and ARG65527 anti-CD161bc / NK1.1 antibody [PK136] (PE).

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