anti-CD52 antibody [HI186] (FITC)

Key features and details

  • 产品描述: FITC-conjugated Mouse Monoclonal antibody [HI186] recognizes CD52
  • 反应物种: Hu
  • 应用: FACS
  • 特异性: The clone HI186 reacts with CD52 (CAMPATH-1), a 21-28 kDa glycoprotein containing a large N-linked carbohydrate moiety; mature CD52 molecule is actually much smaller (approx. 8-9 kDa). CD52 is expressed at high levels on lymphocytes, monocytes/macrophages and in male reproductive tract. HLDA VI; WS Code BP 523HLDA VI; WS Code T 6T-057
  • 宿主: Mouse
  • 克隆: Monoclonal
  • 克隆号: HI186
  • 同位型: IgG2b
  • 靶点名称: CD52
  • Brand:
CAT.NO. : ARG62882
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Product Details
概述
产品描述FITC-conjugated Mouse Monoclonal antibody [HI186] recognizes CD52
反应物种Hu
应用FACS
特异性The clone HI186 reacts with CD52 (CAMPATH-1), a 21-28 kDa glycoprotein containing a large N-linked carbohydrate moiety; mature CD52 molecule is actually much smaller (approx. 8-9 kDa). CD52 is expressed at high levels on lymphocytes, monocytes/macrophages and in male reproductive tract.
HLDA VI; WS Code BP 523
HLDA VI; WS Code T 6T-057
宿主Mouse
克隆Monoclonal
克隆号HI186
同位型IgG2b
靶点名称CD52
抗原物种Human
抗原Human tonsil
偶联标记FITC
別名He5; CAMPATH-1 antigen; Human epididymis-specific protein 5; Cambridge pathology 1 antigen; CDw52; Epididymal secretory protein E5; CDW52; CD antigen CD52
应用说明
应用建议
应用推荐稀释比
FACS20 µl / 10^6 cells
应用说明* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
属性
形式Liquid
纯化说明The purified antibody is conjugated with Fluorescein isothiocyanate (FITC) under optimum conditions. The reagent is free of unconjugated FITC and adjusted for direct use. No reconstitution is necessary.
缓冲液PBS, 15 mM Sodium azide and 0.2% (w/v) high-grade protease free BSA
抗菌剂15 mM Sodium azide
稳定剂0.2% (w/v) high-grade protease free BSA
存放说明Aliquot and store in the dark at 2-8°C. Keep protected from prolonged exposure to light. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
数据库连接

GeneID: 1043 Human CD52

Swiss-port # P31358 Human CAMPATH-1 antigen

基因名称CD52
全名CD52 molecule
背景介绍CD52 (CAMPATH-1, HE5) is a highly glycosylated GPI-anchored 21-28 kDa glycopeptide which is present at high levels on lymphocytes, macrophages, epithelial cells of male reproductive tract and mature sperm. Its 12-amino acid beckbone carries a complex N-linked carbohydrate moiety, which differs between sperm and leukocyte CD52, as well as the GPI anchor does. CD52 can be acquired by sperm cells from seminal plasma, where it is released by epithelial cells. Although CD52 is not an essential T-cell costimulator, its triggering results in activation of normal human T cells. CD52 is a very good target for antibody/complement-mediated cell lysis.
生物功能May play a role in carrying and orienting carbohydrate, as well as having a more specific role. [UniProt]
研究领域Immune System antibody
预测分子量7 kDa
检测图片 (1)
  • ARG62882 anti-CD52 antibody [HI186] (FITC) FACS image

    Flow Cytometry: Human peripheral blood stained with ARG62882 anti-CD52 antibody [HI186] (FITC).

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