anti-CD57 antibody [TB01] (APC)
![anti-CD57 antibody [TB01] (APC)](/upload/image/products/ARG42321_FACS_1_210_205.jpg)
![anti-CD57 antibody [TB01] (APC)](/upload/image/products/ARG42321_FACS_1.jpg)
Key features and details
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- 应用:
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- 靶点名称:
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Brand:
CAT.NO. : ARG42321
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Product Details
概述
| 产品描述 | APC-conjugated Mouse Monoclonal antibody [TB01] recognizes CD57 |
|---|---|
| 反应物种 | Hu |
| 应用 | FACS |
| 特异性 | The mouse monoclonal antibody TB01 recognizes CD57, a carbohydrate extracellular antigen present mainly on NK cells, NK T cells, and in neural tissue. |
| 宿主 | Mouse |
| 克隆 | Monoclonal |
| 克隆号 | TB01 |
| 同位型 | IgM |
| 靶点名称 | CD57 |
| 抗原物种 | Human |
| 抗原 | A pool of neuroblastoma cell lines. |
| 偶联标记 | APC |
| 別名 | Glucuronosyltransferase P; CD57; LEU7; GlcAT-P; GLCATP; HNK1; GlcUAT-P; NK1; Beta-1,3-glucuronyltransferase 1; EC 2.4.1.135; Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1; GLCUATP; UDP-GlcUA:glycoprotein beta-1,3-glucuronyltransferase; NK-1 |
应用说明
| 应用建议 |
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|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purified |
| 缓冲液 | PBS and 15 mM Sodium azide. |
| 抗菌剂 | 15 mM Sodium azide |
| 存放说明 | Aliquot and store in the dark at 2-8°C. Keep protected from prolonged exposure to light. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | Swiss-port # Q9P2W7 Human Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1 |
|---|---|
| 基因名称 | B3GAT1 |
| 全名 | beta-1,3-glucuronyltransferase 1 |
| 背景介绍 | The protein encoded by this gene is a member of the glucuronyltransferase gene family. These enzymes exhibit strict acceptor specificity, recognizing nonreducing terminal sugars and their anomeric linkages. This gene product functions as the key enzyme in a glucuronyl transfer reaction during the biosynthesis of the carbohydrate epitope HNK-1 (human natural killer-1, also known as CD57 and LEU7). Alternate transcriptional splice variants have been characterized. [provided by RefSeq, Jul 2008] |
| 生物功能 | Involved in the biosynthesis of L2/HNK-1 carbohydrate epitope on glycoproteins. Can also play a role in glycosaminoglycan biosynthesis. Substrates include asialo-orosomucoid (ASOR), asialo-fetuin, and asialo-neural cell adhesion molecule. Requires sphingomyelin for activity: stearoyl-sphingomyelin was the most effective, followed by palmitoyl-sphingomyelin and lignoceroyl-sphingomyelin. Activity was demonstrated only for sphingomyelin with a saturated fatty acid and not for that with an unsaturated fatty acid, regardless of the length of the acyl group. [UniProt] |
| 细胞定位 | Isoform 1: Golgi apparatus membrane; Single-pass type II membrane protein. Secreted. Isoform 2: Golgi apparatus membrane; Single-pass type II membrane protein. Endoplasmic reticulum membrane. Secreted. [UniProt] |
| 预测分子量 | 38 kDa |
| 翻译后修饰 | The soluble form derives from the membrane form by proteolytic processing. [UniProt] |
检测图片 (1)
ARG42321 anti-CD57 antibody [TB01] (APC) FACS image
Flow Cytometry: Human peripheral blood stained with ARG42321 anti-CD57 antibody [TB01] (APC).
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