anti-CD6 antibody [MRC OX-52] (FITC)

产品描述: FITC-conjugated Mouse Monoclonal antibody [MRC OX-52] recognizes CD6
反应物种: Rat
应用: FACS
特异性: This monoclonal antibody immunoprecipitates a two chain structure (95, 120 kDa) largely restricted to T lymphocytes and thymocytes. This clone does not inhibit the allogeneic mixed leukocyte response, nor does it inhibit T cytotoxic effector cell function.
宿主: Mouse
克隆: Monoclonal
克隆号: MRC OX-52
同位型: IgG2a
靶点名称: CD6

CAT.NO. : ARG65850

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Size:

100 μl 50 μl

*产品价格可能会有所调整，请以品牌方官网实时更新的价格为准，以确保准确性。

Product Details

概述

产品描述	FITC-conjugated Mouse Monoclonal antibody [MRC OX-52] recognizes CD6
反应物种	Rat
应用	FACS
特异性	This monoclonal antibody immunoprecipitates a two chain structure (95, 120 kDa) largely restricted to T lymphocytes and thymocytes. This clone does not inhibit the allogeneic mixed leukocyte response, nor does it inhibit T cytotoxic effector cell function.
宿主	Mouse
克隆	Monoclonal
克隆号	MRC OX-52
同位型	IgG2a
靶点名称	CD6
抗原物种	Rat
抗原	Rat CD6
偶联标记	FITC
別名	CD antigen CD6; TP120; T-cell differentiation antigen CD6; T12

应用说明

应用建议

应用	推荐稀释比
FACS	Assay-dependent

应用说明

* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

属性

形式	Liquid
纯化	Purified.
缓冲液	PBS (pH 7.2), 0.09% Sodium azide and 1% BSA.
抗菌剂	0.09% Sodium azide
稳定剂	1% BSA
存放说明	Aliquot and store in the dark at 2-8°C. Keep protected from prolonged exposure to light. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项	For laboratory research only, not for drug, diagnostic or other use.

生物信息

基因名称	Cd6
全名	Cd6 molecule
背景介绍	This gene encodes a protein found on the outer membrane of T-lymphocytes as well as some other immune cells. The encoded protein contains three scavenger receptor cysteine-rich (SRCR) domains and a binding site for an activated leukocyte cell adhesion molecule. The gene product is important for continuation of T cell activation. This gene may be associated with susceptibility to multiple sclerosis (PMID: 19525953, 21849685). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011]
生物功能	Involved in cell adhesion. Binds to CD166. [UniProt]
预测分子量	72 kDa
翻译后修饰	After T-cell activation, becomes hyperphosphorylated on Ser and Thr residues and phosphorylated on Tyr residues. Glycosylated.

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