anti-CD6 antibody [MRC OX-52] (FITC)

Key features and details

  • 产品描述: FITC-conjugated Mouse Monoclonal antibody [MRC OX-52] recognizes CD6
  • 反应物种: Rat
  • 应用: FACS
  • 特异性: This monoclonal antibody immunoprecipitates a two chain structure (95, 120 kDa) largely restricted to T lymphocytes and thymocytes. This clone does not inhibit the allogeneic mixed leukocyte response, nor does it inhibit T cytotoxic effector cell function.
  • 宿主: Mouse
  • 克隆: Monoclonal
  • 克隆号: MRC OX-52
  • 同位型: IgG2a
  • 靶点名称: CD6
  • Brand:
CAT.NO. : ARG65850
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Product Details
概述
产品描述FITC-conjugated Mouse Monoclonal antibody [MRC OX-52] recognizes CD6
反应物种Rat
应用FACS
特异性This monoclonal antibody immunoprecipitates a two chain structure (95, 120 kDa) largely restricted to T lymphocytes and thymocytes. This clone does not inhibit the allogeneic mixed leukocyte response, nor does it inhibit T cytotoxic effector cell function.
宿主Mouse
克隆Monoclonal
克隆号MRC OX-52
同位型IgG2a
靶点名称CD6
抗原物种Rat
抗原Rat CD6
偶联标记FITC
別名CD antigen CD6; TP120; T-cell differentiation antigen CD6; T12
应用说明
应用建议
应用推荐稀释比
FACSAssay-dependent
应用说明* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
属性
形式Liquid
纯化Purified.
缓冲液PBS (pH 7.2), 0.09% Sodium azide and 1% BSA.
抗菌剂0.09% Sodium azide
稳定剂1% BSA
存放说明Aliquot and store in the dark at 2-8°C. Keep protected from prolonged exposure to light. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
基因名称Cd6
全名Cd6 molecule
背景介绍This gene encodes a protein found on the outer membrane of T-lymphocytes as well as some other immune cells. The encoded protein contains three scavenger receptor cysteine-rich (SRCR) domains and a binding site for an activated leukocyte cell adhesion molecule. The gene product is important for continuation of T cell activation. This gene may be associated with susceptibility to multiple sclerosis (PMID: 19525953, 21849685). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011]
生物功能Involved in cell adhesion. Binds to CD166. [UniProt]
预测分子量72 kDa
翻译后修饰After T-cell activation, becomes hyperphosphorylated on Ser and Thr residues and phosphorylated on Tyr residues.
Glycosylated.
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