anti-CD62L / L-Selectin antibody [DREG56] (low endotoxin)

产品描述: Azide free and low endotoxin Mouse Monoclonal antibody [DREG56] recognizes CD62L / L-Selectin
反应物种: Hu
应用: FACS, FuncSt, IHC-Fr, IP, WB
特异性: The mouse monoclonal antibody DREG56 recognizes an extracellular epitope of CD62L / L-selectin, a 65-76 kDa cell surface protein, expressed by neutrophils, monocytes, and subsets of T, B, and NK cells, that interacts with specific carbohydrates exposed on activated endothelial cells.
宿主: Mouse
克隆: Monoclonal
克隆号: DREG56
同位型: IgG1
靶点名称: CD62L / L-Selectin

CAT.NO. : ARG42260

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Size:

100 μg

*产品价格可能会有所调整，请以品牌方官网实时更新的价格为准，以确保准确性。

Product Details

概述

产品描述	Azide free and low endotoxin Mouse Monoclonal antibody [DREG56] recognizes CD62L / L-Selectin
反应物种	Hu
应用	FACS, FuncSt, IHC-Fr, IP, WB
特异性	The mouse monoclonal antibody DREG56 recognizes an extracellular epitope of CD62L / L-selectin, a 65-76 kDa cell surface protein, expressed by neutrophils, monocytes, and subsets of T, B, and NK cells, that interacts with specific carbohydrates exposed on activated endothelial cells.
宿主	Mouse
克隆	Monoclonal
克隆号	DREG56
同位型	IgG1
靶点名称	CD62L / L-Selectin
抗原物种	Human
抗原	PMA-activated Human peripheral blood leukocytes.
偶联标记	Un-conjugated
別名	Leukocyte surface antigen Leu-8; Leukocyte adhesion molecule 1; CD antigen CD62L; PLNHR; LSEL; CD62L; Leukocyte-endothelial cell adhesion molecule 1; L-selectin; LAM1; LNHR; TQ1; CD62 antigen-like family member L; gp90-MEL; Lymph node homing receptor; LYAM1; LECAM1; LEU8; LAM-1

应用说明

应用建议

应用说明

* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

属性

形式	Liquid
纯化	Purification with Protein A.
纯化说明	0.2 µm filter sterilized. Endotoxin level is less than 0.01 EU/µg of the protein.
缓冲液	PBS
浓度	1 mg/ml
存放说明	For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项	For laboratory research only, not for drug, diagnostic or other use.

生物信息

数据库连接	GeneID: 6402 Human SELL Swiss-port # P14151 Human L-selectin
基因名称	SELL
全名	selectin L
背景介绍	This gene encodes a cell surface adhesion molecule that belongs to a family of adhesion/homing receptors. The encoded protein contains a C-type lectin-like domain, a calcium-binding epidermal growth factor-like domain, and two short complement-like repeats. The gene product is required for binding and subsequent rolling of leucocytes on endothelial cells, facilitating their migration into secondary lymphoid organs and inflammation sites. Single-nucleotide polymorphisms in this gene have been associated with various diseases including immunoglobulin A nephropathy. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Oct 2009]
生物功能	Calcium-dependent lectin that mediates cell adhesion by binding to glycoproteins on neighboring cells (PubMed:12403782, PubMed:28489325, PubMed:28011641). Mediates the adherence of lymphocytes to endothelial cells of high endothelial venules in peripheral lymph nodes. Promotes initial tethering and rolling of leukocytes in endothelia (PubMed:12403782, PubMed:28011641). [UniProt]
细胞定位	Cell membrane; Single-pass type I membrane protein. [UniProt]
预测分子量	42 kDa

检测图片 (2)

ARG42260 anti-CD62L / L-Selectin antibody [DREG56] (low endotoxin) FACS image
Flow Cytometry: Human peripheral blood stained with ARG42260 anti-CD62L / L-Selectin antibody [DREG56] (low endotoxin) at 1 µg/ml dilution, followed by APC-conjugated Goat anti-Mouse antibody.
ARG42260 anti-CD62L / L-Selectin antibody [DREG56] (low endotoxin) FACS image
Flow Cytometry: Separation of Human CD62L positive lymphocytes (red-filled) from CD62L negative lymphocytes (black-dashed). Human peripheral whole blood stained with ARG42260 anti-CD62L / L-Selectin antibody [DREG56] (low endotoxin) at 1 µg/ml dilution, followed by APC-conjugated Goat anti-Mouse antibody.

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