anti-CD62L / L-Selectin antibody [LT-TD180] (PE)

产品描述: PE-conjugated Mouse Monoclonal antibody [LT-TD180] recognizes CD62L / L-Selectin
反应物种: Hu
应用: FACS
特异性: The clone LT-TD180 reacts with CD62L (L-selectin), a 74-95 kDa single chain type I glycoprotein expressed on most peripheral blood B lymphocytes, T lymphocytes, monocytes and granulocytes; it is also present on a subset of NK cells and certain hematopoietic malignant cells.
宿主: Mouse
克隆: Monoclonal
克隆号: LT-TD180
同位型: IgG1
靶点名称: CD62L / L-Selectin

CAT.NO. : ARG53885

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Size:

100 tests

*产品价格可能会有所调整，请以品牌方官网实时更新的价格为准，以确保准确性。

Product Details

概述

产品描述	PE-conjugated Mouse Monoclonal antibody [LT-TD180] recognizes CD62L / L-Selectin
反应物种	Hu
应用	FACS
特异性	The clone LT-TD180 reacts with CD62L (L-selectin), a 74-95 kDa single chain type I glycoprotein expressed on most peripheral blood B lymphocytes, T lymphocytes, monocytes and granulocytes; it is also present on a subset of NK cells and certain hematopoietic malignant cells.
宿主	Mouse
克隆	Monoclonal
克隆号	LT-TD180
同位型	IgG1
靶点名称	CD62L / L-Selectin
抗原	Peripheral blood leukocytes
偶联标记	PE
別名	Leukocyte surface antigen Leu-8; Leukocyte adhesion molecule 1; CD antigen CD62L; PLNHR; LSEL; CD62L; Leukocyte-endothelial cell adhesion molecule 1; L-selectin; LAM1; LNHR; TQ1; CD62 antigen-like family member L; gp90-MEL; Lymph node homing receptor; LYAM1; LECAM1; LEU8; LAM-1

应用说明

应用建议

应用	推荐稀释比
FACS	20 µl / 10^6 cells

应用说明

* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

属性

形式	Liquid
纯化说明	The purified antibody is conjugated with R-Phycoerythrin (PE) under optimum conditions. The conjugate is purified by size-exclusion chromatography and adjusted for direct use. No reconstitution is necessary.
缓冲液	PBS, 15 mM Sodium azide and 0.2% (w/v) high-grade protease free BSA
抗菌剂	15 mM Sodium azide
稳定剂	0.2% (w/v) high-grade protease free BSA
存放说明	Aliquot and store in the dark at 2-8°C. Keep protected from prolonged exposure to light. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项	For laboratory research only, not for drug, diagnostic or other use.

生物信息

数据库连接	GeneID: 6402 Human SELL Swiss-port # P14151 Human L-selectin
基因名称	SELL
全名	selectin L
背景介绍	CD62L (L-selectin) is an adhesion glycoprotein that is constitutively expressed on the cell surface of leukocytes and mediates their homing to inflammatory sites and peripheral lymph nodes by enabling rolling along the venular wall. CD62L is also involved in activation-induced neutrophil aggregation. Activation-dependent CD62L shedding, however, counteracts neutrophil rolling. CD62L has also signaling roles including enhance of chemokine receptor expression. Similarly to CD62P, the major ligand of CD62L is PSGL-1 (P-selectin glycoprotein ligand-1).
生物功能	Cell surface adhesion protein. Mediates the adherence of lymphocytes to endothelial cells of high endothelial venules in peripheral lymph nodes. Promotes initial tethering and rolling of leukocytes in endothelia. [UniProt]
研究领域	Cell Biology and Cellular Response antibody; Developmental Biology antibody; Immune System antibody; Signaling Transduction antibody
预测分子量	42 kDa

检测图片 (1)

ARG53885 anti-CD62L / L-Selectin antibody [LT-TD180] (PE) FACS image
Flow Cytometry: Human peripheral blood cells stained with ARG53885 anti-CD62L / L-Selectin antibody [LT-TD180] (PE).

参考文献

克隆号文献

Identification of an MSI-H tumor-specific cytotoxic T cell epitope generated by the (-1) frame of U79260(FTO).

Linnebacher M et al.
J Biomed Biotechnol., (2010)