anti-CD62L / L-Selectin antibody [MEL-14] (FITC)
![anti-CD62L / L-Selectin antibody [MEL-14] (FITC)](/upload/image/products/ARG62909_FACS_161230_210_205.jpg)
![anti-CD62L / L-Selectin antibody [MEL-14] (FITC)](/upload/image/products/ARG62909_FACS_161230.jpg)
Key features and details
- 产品描述:
- 反应物种:
- 应用:
- 宿主:
- 克隆:
- 克隆号:
- 同位型:
- 靶点名称:
- 抗原物种:
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Brand:
Product Details
| 产品描述 | FITC-conjugated Rat Monoclonal antibody [MEL-14] recognizes CD62L / L-Selectin |
|---|---|
| 反应物种 | Ms |
| 应用 | BL, FACS, IHC-Fr |
| 宿主 | Rat |
| 克隆 | Monoclonal |
| 克隆号 | MEL-14 |
| 同位型 | IgG2a, kappa |
| 靶点名称 | CD62L / L-Selectin |
| 抗原物种 | Mouse |
| 抗原 | C3H/eb cloned mouse B cell lymphoma 38C-13 |
| 偶联标记 | FITC |
| 別名 | Leukocyte surface antigen Leu-8; Leukocyte adhesion molecule 1; CD antigen CD62L; PLNHR; LSEL; CD62L; Leukocyte-endothelial cell adhesion molecule 1; L-selectin; LAM1; LNHR; TQ1; CD62 antigen-like family member L; gp90-MEL; Lymph node homing receptor; LYAM1; LECAM1; LEU8; LAM-1 |
| 应用建议 |
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|---|---|---|---|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
| 形式 | Liquid |
|---|---|
| 缓冲液 | PBS and 0.1% Sodium azide. |
| 抗菌剂 | 0.1% Sodium azide |
| 浓度 | 0.5 mg/ml |
| 存放说明 | Aliquot and store in the dark at 2-8°C. Keep protected from prolonged exposure to light. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
| 数据库连接 | |
|---|---|
| 基因名称 | Sell |
| 全名 | selectin, lymphocyte |
| 背景介绍 | CD62L (L-selectin) is an adhesion glycoprotein that is constitutively expressed on the cell surface of leukocytes and mediates their homing to inflammatory sites and peripheral lymph nodes by enabling rolling along the venular wall. CD62L is also involved in activation-induced neutrophil aggregation. Activation-dependent CD62L shedding, however, counteracts neutrophil rolling. CD62L has also signaling roles including enhance of chemokine receptor expression. Similarly to CD62P, the major ligand of CD62L is PSGL-1 (P-selectin glycoprotein ligand-1). _x000D_ |
| 生物功能 | Cell surface adhesion protein. Mediates the adherence of lymphocytes to endothelial cells of high endothelial venules in peripheral lymph nodes. Promotes initial tethering and rolling of leukocytes in endothelia (By similarity). [UniProt] |
| 研究领域 | Cell Biology and Cellular Response antibody; Developmental Biology antibody; Immune System antibody; Signaling Transduction antibody |
| 预测分子量 | 42 kDa |
ARG62909 anti-CD62L / L-Selectin antibody [MEL-14] (FITC) FACS image
Flow Cytometry: BALB/c Mouse splenocytes stained with ARG62909 anti-CD62L / L-Selectin antibody [MEL-14] (FITC) and ARG20819 anti-CD3e antibody [C363.29B] (PE).
克隆号文献
Coadministration of polyinosinic:polycytidylic acid and immunostimulatory complexes modifies antigen processing in dendritic cell subsets and enhances HIV gag-specific T cell immunity.
ICC/IF /
Comparative analysis of the magnitude, quality, phenotype, and protective capacity of simian immunodeficiency virus gag-specific CD8+ T cells following human-, simian-, and chimpanzee-derived recombinant adenoviral vector immunization.
IL-10 restricts memory T cell inflation during cytomegalovirus infection.
FACS / Mouse
TLR-mediated loss of CD62L focuses B cell traffic to the spleen during Salmonella typhimurium infection.
FACS / Mouse
Distribution of MEL-14+ cells in various lymphoid tissues.
FACS, FuncSt / Mouse
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