anti-CD62P / P-Selectin antibody
Key features and details
- 产品描述:
- 反应物种:
- 应用:
- 宿主:
- 克隆:
- 同位型:
- 靶点名称:
- 抗原:
- 偶联标记:
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Brand:
CAT.NO. : ARG43816
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Product Details
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes CD62P / P-Selectin. |
|---|---|
| 反应物种 | Ms, Rat |
| 应用 | ELISA, FACS, ICC/IF, IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | CD62P / P-Selectin |
| 抗原 | Recombinant protein around aa. 40-270 of mouse CD62P. |
| 偶联标记 | Un-conjugated |
| Protein Full name | P-selectin |
| 別名 | SELP; Selectin P; PADGEM; GMP140; CD62P; CD62; PSEL; GRMP; Platelet Activation Dependent Granule-External Membrane Protein; Selectin P Granule Membrane Protein 140kDa; Antigen CD62; Leukocyte Endothelial Cell Adhesion Molecule 3; CD62 Antigen Like Family Member P; Granule Membrane Protein 140kDa; Granule Membrane Protein 140; P Selectin; GMP 140; LECAM3; Selectin P Granule Membrane Protein 140kD; Antigen CD62 Platelet Alpha-Granule Membrane Protein; Granulocyte Membrane Protein; CD62P Antigen; Antigen CD62; GMRP |
应用说明
| 应用建议 |
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属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purification with immunogen. |
| 缓冲液 | 0.9% NaCl, 0.2% Na2HPO4, 0.05% Sodium azide and 4% Trehalose. |
| 抗菌剂 | 0.05% Sodium azide |
| 稳定剂 | 4% Trehalose |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | SELP |
| 全名 | Selectin P |
| 背景介绍 | This gene encodes a 140 kDa protein that is stored in the alpha-granules of platelets and Weibel-Palade bodies of endothelial cells. This protein redistributes to the plasma membrane during platelet activation and degranulation and mediates the interaction of activated endothelial cells or platelets with leukocytes. The membrane protein is a calcium-dependent receptor that binds to sialylated forms of Lewis blood group carbohydrate antigens on neutrophils and monocytes. Alternative splice variants may occur but are not well documented. |
| 生物功能 | Ca2+-dependent receptor for myeloid cells that binds to carbohydrates on neutrophils and monocytes. Mediates the interaction of activated endothelial cells or platelets with leukocytes. The ligand recognized is sialyl-Lewis X. Mediates rapid rolling of leukocyte rolling over vascular surfaces during the initial steps in inflammation through interaction with SELPLG. [UniProt] |
| 细胞定位 | Cell membrane |
| 预测分子量 | ~ 140 kDa |
| 翻译后修饰 | Disulfide bond, Glycoprotein, Lipoprotein, Palmitate |
检测图片 (2)
ARG43816 anti-CD62P / P-Selectin antibody WB image
Western blot: Mouse heart and Rat heart cell tissue stained with ARG43816 anti-CD62P / P-Selectin antibody at 1:1000 dilution.
ARG43816 anti-CD62P / P-Selectin antibody FACS image
Flow Cytometry: RAW264.7 cells stained with ARG43816 anti-CD62P / P-Selectin antibody at1 :50 dilution.
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