anti-CD66a + CD66c + CD66d antibody [YTH71.3]

Key features and details

  • 产品描述: Rat Monoclonal antibody [YTH71.3] recognizes CD66a + CD66c + CD66dThis antibody recognizes 3 members of the human CD66 family, namely CD66a, CD66c and CD66d. CD66 members are expressed by human neutrophils and cells of the colon where it is down regulated in some cases of colon carcinoma (Neumaier et al. 2012). CD66a is also expressed in the human alveolar adenocarcinoma cell line A549 and may play a role in Moraxella catarrhalis induced apoptosis of pulmonary epithlial cells in diseases including COPD and emphysema (N'Guessan et al. 2007).
  • 反应物种: Hu, R. Mk
  • 不反应物种: Ms
  • 应用: FACS, IHC-Fr
  • 宿主: Rat
  • 克隆: Monoclonal
  • 克隆号: YTH71.3
  • 同位型: IgG2a
  • 靶点名称: CD66a + CD66c + CD66d
  • Brand:
CAT.NO. : ARG22498
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Product Details
概述
产品描述Rat Monoclonal antibody [YTH71.3] recognizes CD66a + CD66c + CD66d
This antibody recognizes 3 members of the human CD66 family, namely CD66a, CD66c and CD66d. CD66 members are expressed by human neutrophils and cells of the colon where it is down regulated in some cases of colon carcinoma (Neumaier et al. 2012). CD66a is also expressed in the human alveolar adenocarcinoma cell line A549 and may play a role in Moraxella catarrhalis induced apoptosis of pulmonary epithlial cells in diseases including COPD and emphysema (N'Guessan et al. 2007).
反应物种Hu, R. Mk
不反应物种Ms
应用FACS, IHC-Fr
宿主Rat
克隆Monoclonal
克隆号YTH71.3
同位型IgG2a
靶点名称CD66a + CD66c + CD66d
抗原物种Human
抗原Human lymphocytes
偶联标记Un-conjugated
別名Normal cross-reacting antigen; Carcinoembryonic antigen-related cell adhesion molecule 6; CEAL; CD66c; CD antigen CD66c; NCA; Non-specific crossreacting antigen
应用说明
应用建议
应用推荐稀释比
FACSAssay-dependent
IHC-FrAssay-dependent
应用说明FACS: Use 10ul of the suggested working dilution to label 10^6 cells in 100ul.
* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
属性
形式Liquid
纯化Purification with Protein G.
缓冲液PBS and 0.09% Sodium azide
抗菌剂0.09% Sodium azide
浓度1 mg/ml
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
数据库连接

GeneID: 4680 Human CEACAM6

Swiss-port # P40199 Human Carcinoembryonic antigen-related cell adhesion molecule 6

基因名称CEACAM6
全名carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
背景介绍This gene encodes a protein that belongs to the carcinoembryonic antigen (CEA) family whose members are glycosyl phosphatidyl inositol (GPI) anchored cell surface glycoproteins. Members of this family play a role in cell adhesion and are widely used as tumor markers in serum immunoassay determinations of carcinoma. This gene affects the sensitivity of tumor cells to adenovirus infection. The protein encoded by this gene acts as a receptor for adherent-invasive E. coli adhesion to the surface of ileal epithelial cells in patients with Crohn's disease. This gene is clustered with genes and pseudogenes of the cell adhesion molecules subgroup of the CEA family on chromosome 19. [provided by RefSeq, Apr 2014]
预测分子量37 kDa
检测图片 (1)
  • ARG22498 anti-CD66a + CD66c + CD66d antibody [YTH71.3] FACS image

    Flow Cytometry: Human peripheral blood granulocytes stained with ARG22498 anti-CD66a + CD66c + CD66d antibody [YTH71.3].

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