anti-CD66b antibody [80H3]

Key features and details

  • 产品描述: Mouse Monoclonal antibody [80H3] recognizes CD66bMouse anti Human CD66b antibody, clone 80H3 reacts with the CEACAM8 or CGM6 gene product, from the carcinoembryonic gene family. The CEACAM8 gene product is called CD66b, Non-specific cross-reacting antigen NCA-95 or Carcinoembryonic antigen CGM6. CD66b is a 286 amino acid mature ~95-100 kDa GPI anchored molecule with an N-terminal 34 amino acid signal peptide and a 29 amino acid C-terminal propeptide, shed in the mature form. CD66b is expressed strongly by mature granulocytes and metamyelocytes, and weakly by bone marrow myelocytes. CD66b is not expressed by peripheral blood monocytes or lymphocytes.
  • 反应物种: Hu
  • 应用: FACS, FuncSt, IHC-Fr, WB
  • 宿主: Mouse
  • 克隆: Monoclonal
  • 克隆号: 80H3
  • 同位型: IgG1
  • 靶点名称: CD66b
  • 抗原物种: Human
  • Brand:
CAT.NO. : ARG22989
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Product Details
概述
产品描述Mouse Monoclonal antibody [80H3] recognizes CD66b
Mouse anti Human CD66b antibody, clone 80H3 reacts with the CEACAM8 or CGM6 gene product, from the carcinoembryonic gene family. The CEACAM8 gene product is called CD66b, Non-specific cross-reacting antigen NCA-95 or Carcinoembryonic antigen CGM6. CD66b is a 286 amino acid mature ~95-100 kDa GPI anchored molecule with an N-terminal 34 amino acid signal peptide and a 29 amino acid C-terminal propeptide, shed in the mature form. CD66b is expressed strongly by mature granulocytes and metamyelocytes, and weakly by bone marrow myelocytes. CD66b is not expressed by peripheral blood monocytes or lymphocytes.
反应物种Hu
应用FACS, FuncSt, IHC-Fr, WB
宿主Mouse
克隆Monoclonal
克隆号80H3
同位型IgG1
靶点名称CD66b
抗原物种Human
抗原Human leucocytes from individuals with CML.
偶联标记Un-conjugated
別名CD67; NCA-95; CD67 antigen; CGM6; CD66b; Carcinoembryonic antigen-related cell adhesion molecule 8; Carcinoembryonic antigen CGM6; Non-specific cross-reacting antigen NCA-95; CD antigen CD66b
应用说明
应用建议
应用推荐稀释比
FACS1:50 - 1:100
FuncStAssay-dependent
IHC-Fr1:25 - 1:100
WBAssay-dependent
应用说明Functional study: This product contains sodium azide, removal by dialysis is recommended prior to use in functional assays.
IHC-Fr: The epitope recognised by this antibody is reported to be sensitive to formaldehyde fixation and tissue processing. Arigo recommends the use of acetone fixation for frozen sections.
FACS: Use 10 µl of the suggested working dilution to label 5 x 10^5 cells or 100 µl whole blood.
* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
属性
形式Liquid
纯化Purification with Protein A.
缓冲液PBS, 0.09% Sodium azide and 0.5% BSA
抗菌剂0.09% Sodium azide
稳定剂0.5% BSA
浓度1 mg/ml
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
数据库连接

GeneID: 1088 Human CEACAM8

Swiss-port # P31997 Human Carcinoembryonic antigen-related cell adhesion molecule 8

基因名称CEACAM8
全名carcinoembryonic antigen-related cell adhesion molecule 8
预测分子量38 kDa
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