anti-CD7 antibody [MEM-186] (APC)

Key features and details

  • 产品描述: APC-conjugated Mouse Monoclonal antibody [MEM-186] recognizes CD7
  • 反应物种: Hu
  • 应用: FACS
  • 特异性: The clone MEM-186 reacts with CD7, a 40 kD type I transmembrane glycoprotein expressed on peripheral blood T lymphocytes, NK-cells, hematopoietic progenitors, monocytes (weakly) and also on acute lymphocytic leukemia.HLDA VI; WS Code T 6T-015
  • 宿主: Mouse
  • 克隆: Monoclonal
  • 克隆号: MEM-186
  • 同位型: IgG1
  • 靶点名称: CD7
  • Brand:
CAT.NO. : ARG53893
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Product Details
概述
产品描述APC-conjugated Mouse Monoclonal antibody [MEM-186] recognizes CD7
反应物种Hu
应用FACS
特异性The clone MEM-186 reacts with CD7, a 40 kD type I transmembrane glycoprotein expressed on peripheral blood T lymphocytes, NK-cells, hematopoietic progenitors, monocytes (weakly) and also on acute lymphocytic leukemia.
HLDA VI; WS Code T 6T-015
宿主Mouse
克隆Monoclonal
克隆号MEM-186
同位型IgG1
靶点名称CD7
抗原物种Human
抗原Human acute myelogenous leukaemia cell line KG-1.
偶联标记APC
別名TP41; Tp40; T-cell antigen CD7; CD antigen CD7; T-cell leukemia antigen; LEU-9; T-cell surface antigen Leu-9; GP40
应用说明
应用建议
应用推荐稀释比
FACS10 µl / 10^6 cells
应用说明* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
属性
形式Liquid
纯化说明The purified antibody is conjugated with cross-linked Allophycocyanin (APC) under optimum conditions. The conjugate is purified by size-exclusion chromatography and adjusted for direct use. No reconstitution is necessary.
缓冲液PBS, 15 mM Sodium azide and 0.2% (w/v) high-grade protease free BSA
抗菌剂15 mM Sodium azide
稳定剂0.2% (w/v) high-grade protease free BSA
存放说明Aliquot and store in the dark at 2-8°C. Keep protected from prolonged exposure to light. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
数据库连接

GeneID: 924 Human CD7

Swiss-port # P09564 Human T-cell antigen CD7

基因名称CD7
全名CD7 molecule
背景介绍CD7, also known as gp40, is a member of the immunoglobulin superfamily found on T cells, NK cells, thymocytes, hematopoietic progenitors, and monocytes (weakly). CD7 is also expressed on acute lymphocytic leukemia (ALL). CD7 crosslinking induces a calcium flux in T lymphocytes, presumably as a result of cytoplasmic domain association with PI3-kinase. CD7 co-stimulation can induce cytokine secretion and modulate cellular adhesion. A ligand of CD7, epithelial cell secreted protein K12, is produced in thymus to regulate thymocyte signaling and cytokine release. In lung microvascular endothelial cells CD7 serves as an IgM Fc receptor. Expression of CD7 is an important marker used in leukemia diagnostics.
生物功能Not yet known. [UniProt]
研究领域Immune System antibody
预测分子量25 kDa
检测图片 (1)
  • ARG53893 anti-CD7 antibody [MEM-186] (APC) FACS image

    Flow Cytometry: Human peripheral blood cells stained with ARG53893 anti-CD7 antibody [MEM-186] (APC).

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