anti-CD72 antibody [10.1.D2] (Biotin)
CAT.NO. : ARG20949
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概述
产品描述 | Biotin-conjugated Mouse Monoclonal antibody [10.1.D2] recognizes CD72 |
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反应物种 | Ms |
应用 | BL, Cell-Act , FACS |
特异性 | Mouse CD72.1. The clone 10.1.D2 blocks binding of CD5 to CD72 on the B cell surface which leads to inhibition of the positive signal resulting from CD5/CD72 pairing. However, 10.1.D2 can itself trigger a positive signal by binding CD72. |
宿主 | Mouse |
克隆 | Monoclonal |
克隆号 | 10.1.D2 |
同位型 | IgG2b, kappa |
靶点名称 | CD72 |
抗原物种 | Mouse |
抗原 | DBA/2 mouse spleen cells |
偶联标记 | Biotin |
別名 | CD antigen CD72; LYB2; B-cell differentiation antigen CD72; Lyb-2; CD72b |
应用说明
应用建议 |
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应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
形式 | Liquid |
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缓冲液 | PBS and 0.1% Sodium azide. |
抗菌剂 | 0.1% Sodium azide |
浓度 | 0.5 mg/ml |
存放说明 | Aliquot and store in the dark at 2-8°C. Keep protected from prolonged exposure to light. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
数据库连接 | Swiss-port # P21855 Mouse B-cell differentiation antigen CD72 |
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基因名称 | CD72 |
全名 | CD72 antigen |
生物功能 | Plays a role in B-cell proliferation and differentiation. [UniProt] |
预测分子量 | 40 kDa |
翻译后修饰 | Phosphorylated upon engagement of the B-cell receptor, probably by LYN or SYK. Phosphorylation at Tyr-7 is important for interaction with PTPN6/SHP-1 (By similarity). |
检测图片 (1)
ARG20949 anti-CD72 antibody [10.1.D2] (Biotin) FACS image
Flow Cytometry: DBA/2 Mouse splenocytes stained with ARG20949 anti-CD72 antibody [10.1.D2] (Biotin) and ARG20852 anti-CD19 antibody [6D5] (PE) followed by Streptavidin (FITC).
