anti-CD75 / ST6GAL1 antibody [LN1]

Key features and details

  • 产品描述: Mouse Monoclonal antibody [LN1] recognizes CD75 / ST6GAL1
  • 反应物种: Hu
  • 应用: FACS, ICC/IF, IHC-P
  • 特异性: Reacts with RBC precursors of bone marrow, ductal and ciliated epithelial cells of kidney, breast, prostate, pancreas, lung, and with glioblastomas, astrocytomas, and Reed Sternberg cells in lymphocyte predominant Hodgkin’s disease. It is shown to be a helpful antibody for ascribing a B-cell phenotype in known lymphoid tissues.
  • 宿主: Mouse
  • 克隆: Monoclonal
  • 克隆号: LN1
  • 同位型: IgM
  • 靶点名称: CD75 / ST6GAL1
  • Brand:
CAT.NO. : ARG62441
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Product Details
概述
产品描述Mouse Monoclonal antibody [LN1] recognizes CD75 / ST6GAL1
反应物种Hu
应用FACS, ICC/IF, IHC-P
特异性Reacts with RBC precursors of bone marrow, ductal and ciliated epithelial cells of kidney, breast, prostate, pancreas, lung, and with glioblastomas, astrocytomas, and Reed Sternberg cells in lymphocyte predominant Hodgkin’s disease. It is shown to be a helpful antibody for ascribing a B-cell phenotype in known lymphoid tissues.
宿主Mouse
克隆Monoclonal
克隆号LN1
同位型IgM
靶点名称CD75 / ST6GAL1
抗原物种Human
抗原Tissue, cells or virus corresponding to Human CD75. Nuclei from pokeweed mitogen-stimulated peripheral blood lymphocytes.
偶联标记Un-conjugated
別名SIAT1; CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,6-sialyltransferase 1; B-cell antigen CD75; Sialyltransferase 1; ST6Gal I; Beta-galactoside alpha-2,6-sialyltransferase 1; EC 2.4.99.1; ST6N; Alpha 2,6-ST 1; ST6GalI
应用说明
应用建议
应用推荐稀释比
FACS5 - 10 µl/10^6 cells
ICC/IF1:25 - 1:50
IHC-P1:50 - 1:100
应用说明* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
属性
形式Liquid
缓冲液1X PBS buffer with
抗菌剂
浓度2 mg/ml
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
数据库连接

GeneID: 6480 Human ST6GAL1

Swiss-port # P15907 Human Beta-galactoside alpha-2,6-sialyltransferase 1

基因名称ST6GAL1
全名ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
背景介绍This gene encodes a member of glycosyltransferase family 29. The encoded protein is a type II membrane protein that catalyzes the transfer of sialic acid from CMP-sialic acid to galactose-containing substrates. The protein, which is normally found in the Golgi but can be proteolytically processed to a soluble form, is involved in the generation of the cell-surface carbohydrate determinants and differentiation antigens HB-6, CD75, and CD76. This gene has been incorrectly referred to as CD75. Three transcript variants encoding two different isoforms have been described. [provided by RefSeq, Aug 2009]
生物功能Transfers sialic acid from CMP-sialic acid to galactose-containing acceptor substrates. [UniProt]
细胞定位Golgi Apparatus; Golgi stack; Golgi stack membrane; single-pass type II membrane protein. Membrane-bound form in trans cisternae of Golgi. Secreted protein; body fluid.
研究领域Immune System antibody; Signaling Transduction antibody
预测分子量47 kDa
翻译后修饰The soluble form derives from the membrane form by proteolytic processing.
The HB-6, CDW75, and CD76 differentiation antigens are cell-surface carbohydrate determinants generated by this enzyme.
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