anti-CD80 antibody [1G10] (PE-Cyanine 5)
![anti-CD80 antibody [1G10] (PE-Cyanine 5)](/upload/image/products/ARG20956_FACS_1_190906_210_205.jpg)
![anti-CD80 antibody [1G10] (PE-Cyanine 5)](/upload/image/products/ARG20956_FACS_1_190906.jpg)
Key features and details
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- 靶点名称:
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Brand:
CAT.NO. : ARG20956
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Product Details
概述
| 产品描述 | PE-Cyanine 5-conjugated Rat Monoclonal antibody [1G10] recognizes CD80 |
|---|---|
| 反应物种 | Ms |
| 应用 | BL, FACS |
| 特异性 | Mouse CD80. The clone 1G10 blocks binding of CTLA-4 to CD80 but it does not block stimulation of T cells by natural antigen-presenting cells. |
| 宿主 | Rat |
| 克隆 | Monoclonal |
| 克隆号 | 1G10 |
| 同位型 | IgG2a, kappa |
| 靶点名称 | CD80 |
| 抗原物种 | Mouse |
| 抗原 | Activated 5C2 cells |
| 偶联标记 | PE-Cyanine 5 |
| 別名 | B7.1; CTLA-4 counter-receptor B7.1; CD28LG; T-lymphocyte activation antigen CD80; B7-1; CD28LG1; B7; LAB7; Activation B7-1 antigen; CD antigen CD80; BB1 |
应用说明
| 应用建议 |
| ||||||
|---|---|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 缓冲液 | PBS, 0.1% Sodium azide and Sucrose. |
| 抗菌剂 | 0.1% Sodium azide |
| 稳定剂 | Sucrose |
| 浓度 | 0.1 mg/ml |
| 存放说明 | Aliquot and store in the dark at 2-8°C. Keep protected from prolonged exposure to light. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | Swiss-port # Q00609 Mouse T-lymphocyte activation antigen CD80 |
|---|---|
| 基因名称 | CD80 |
| 全名 | CD80 antigen |
| 背景介绍 | The protein encoded by this gene is a membrane receptor that is activated by the binding of CD28 or CTLA-4. The activated protein induces T-cell proliferation and cytokine production. This protein can act as a receptor for adenovirus subgroup B and may play a role in lupus neuropathy. [provided by RefSeq, Aug 2011] |
| 生物功能 | Involved in the costimulatory signal essential for T-lymphocyte activation. T-cell proliferation and cytokine production is induced by the binding of CD28, binding to CTLA-4 has opposite effects and inhibits T-cell activation. [UniProt] |
| 预测分子量 | 33 kDa |
检测图片 (1)
ARG20956 anti-CD80 antibody [1G10] (PE-Cyanine 5) FACS image
Flow Cytometry: DBA/2 Mouse mastocytoma cell line P815 (negative control) and mCD80-Ig transfected P815 cells stained with ARG20956 anti-CD80 antibody [1G10] (PE-Cyanine 5).
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