anti-CD90 / Thy 1 antibody [5E10] (APC)

Key features and details

  • 产品描述: APC-conjugated Mouse Monoclonal antibody [5E10] recognizes CD90 / Thy 1
  • 反应物种: Hu, Dog, NHuPrm, Pig
  • 应用: FACS
  • 特异性: The clone 5E10 recognizes CD90/Thy-1, a GPI-anchored cell surface glycoprotein expressed predominantly on thymocytes, hematopoietic stem cells and neurons.
  • 宿主: Mouse
  • 克隆: Monoclonal
  • 克隆号: 5E10
  • 同位型: IgG1
  • 靶点名称: CD90 / Thy 1
  • Brand:
CAT.NO. : ARG54207
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Product Details
概述
产品描述APC-conjugated Mouse Monoclonal antibody [5E10] recognizes CD90 / Thy 1
反应物种Hu, Dog, NHuPrm, Pig
应用FACS
特异性The clone 5E10 recognizes CD90/Thy-1, a GPI-anchored cell surface glycoprotein expressed predominantly on thymocytes, hematopoietic stem cells and neurons.
宿主Mouse
克隆Monoclonal
克隆号5E10
同位型IgG1
靶点名称CD90 / Thy 1
抗原HEL erythroleukemia cells.
偶联标记APC
別名Thy-1 membrane glycoprotein; Thy-1 antigen; CD antigen CD90; CDw90; CD90
应用说明
应用建议
应用推荐稀释比
FACS10 µl / 10^6 cells
应用说明* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
属性
形式Liquid
纯化说明The purified antibody is conjugated with cross-linked Allophycocyanin (APC) under optimum conditions. The conjugate is purified by size-exclusion chromatography and adjusted for direct use. No reconstitution is necessary.
缓冲液PBS, 15 mM Sodium azide and 0.2% (w/v) high-grade protease free BSA
抗菌剂15 mM Sodium azide
稳定剂0.2% (w/v) high-grade protease free BSA
存放说明Aliquot and store in the dark at 2-8°C. Keep protected from prolonged exposure to light. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
数据库连接

GeneID: 7070 Human THY1

Swiss-port # P04216 Human Thy-1 membrane glycoprotein

基因名称THY1
全名Thy-1 cell surface antigen
背景介绍CD90 (Thy-1) is an 18-35 kDa GPI-anchored plasma membrane glycoprotein expressed in many cell types, such as in hematopoietic cells and neurons, connective tissues, various fibroblast and stromal cell lines, tumor endothelial cell lines and other. It is involved in T cell activation, cellular adhesion, proliferation and migration, neurite outgrowth, wound healing, apoptosis, and fibrosis. CD90 participates in multiple signaling cascades and its effects are tissue- and cell type-specific. It often functions as an important regulator of cell-cell and cell-matrix interactions.
生物功能May play a role in cell-cell or cell-ligand interactions during synaptogenesis and other events in the brain. [UniProt]
研究领域Developmental Biology antibody; Immune System antibody; Neuroscience antibody
预测分子量18 kDa
检测图片 (1)
  • ARG54207 anti-CD90 / Thy 1 antibody [5E10] (APC) FACS image

    Flow Cytometry: Separation of Jurkat cells (red) from SP2 cells (blue). Cells were stained with ARG54207 anti-CD90 / Thy 1 antibody [5E10] (APC).

参考文献

克隆号文献

Amniotic fluid-derived mesenchymal stem cells prevent fibrosis and preserve renal function in a preclinical porcine model of kidney transplantation.

Baulier E et al.
Stem Cells Transl Med.,  (2014)

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Immunopathogenic role of TH1 cells in autoimmune diabetes: evidence from a T1 and T2 doubly transgenic non-obese diabetic mouse model.

Hung JT et al.
J Autoimmun.,  (2005)

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Expression of Thy-1 on human hematopoietic progenitor cells.

Craig W et al.
J Exp Med.,  (1993)

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Thy-1 expression is linked to functional properties of primitive hematopoietic progenitor cells from human umbilical cord blood.

Mayani H et al.
Blood.,  (1994)

publication_link

 

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