anti-CD90 / Thy 1 antibody [5E10] (azide free)

Key features and details

  • 产品描述: Azide free Mouse Monoclonal antibody [5E10] recognizes CD90 / Thy 1
  • 反应物种: Hu, Dog, NHuPrm, Pig
  • 应用: CyTOF®-candidate, FACS, ICC/IF, IHC-Fr, IP, WB
  • 特异性: The clone 5E10 recognizes CD90/Thy-1, a GPI-anchored cell surface glycoprotein expressed predominantly on thymocytes, hematopoietic stem cells and neurons.
  • 宿主: Mouse
  • 克隆: Monoclonal
  • 克隆号: 5E10
  • 同位型: IgG1
  • 靶点名称: CD90 / Thy 1
  • Brand:
CAT.NO. : ARG65399
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Product Details
概述
产品描述Azide free Mouse Monoclonal antibody [5E10] recognizes CD90 / Thy 1
反应物种Hu, Dog, NHuPrm, Pig
应用CyTOF®-candidate, FACS, ICC/IF, IHC-Fr, IP, WB
特异性The clone 5E10 recognizes CD90/Thy-1, a GPI-anchored cell surface glycoprotein expressed predominantly on thymocytes, hematopoietic stem cells and neurons.
宿主Mouse
克隆Monoclonal
克隆号5E10
同位型IgG1
靶点名称CD90 / Thy 1
抗原HEL erythroleukemia cells.
偶联标记Un-conjugated
別名Thy-1 membrane glycoprotein; Thy-1 antigen; CD antigen CD90; CDw90; CD90
应用说明
应用建议
应用推荐稀释比
CyTOF®-candidateAssay-dependent
FACS1 - 3 µg/ml
ICC/IFAssay-dependent
IHC-Fr5 - 10 µg/ml
IPAssay-dependent
WBAssay-dependent
应用说明* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
属性
形式Liquid
纯化Purification with Protein A.
纯化说明Preserved by filter sterilization.
纯度> 95% (by SDS-PAGE)
缓冲液PBS (pH 7.4)
浓度1 mg/ml
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
数据库连接

GeneID: 7070 Human THY1

Swiss-port # P04216 Human Thy-1 membrane glycoprotein

基因名称THY1
全名Thy-1 cell surface antigen
背景介绍CD90 (Thy-1) is an 18-35 kDa GPI-anchored plasma membrane glycoprotein expressed in many cell types, such as in hematopoietic cells and neurons, connective tissues, various fibroblast and stromal cell lines, tumor endothelial cell lines and other. It is involved in T cell activation, cellular adhesion, proliferation and migration, neurite outgrowth, wound healing, apoptosis, and fibrosis. CD90 participates in multiple signaling cascades and its effects are tissue- and cell type-specific. It often functions as an important regulator of cell-cell and cell-matrix interactions.
生物功能May play a role in cell-cell or cell-ligand interactions during synaptogenesis and other events in the brain. [UniProt]
产品亮点Related products:
CD90 antibodies; Anti-Mouse IgG secondary antibodies;
Related news:
CyTOF-candidate Antibodies
研究领域Developmental Biology antibody; Immune System antibody; Neuroscience antibody
预测分子量18 kDa
参考文献

克隆号文献

Amniotic fluid-derived mesenchymal stem cells prevent fibrosis and preserve renal function in a preclinical porcine model of kidney transplantation.

Baulier E et al.
Stem Cells Transl Med.,  (2014)

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Immunopathogenic role of TH1 cells in autoimmune diabetes: evidence from a T1 and T2 doubly transgenic non-obese diabetic mouse model.

Hung JT et al.
J Autoimmun.,  (2005)

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Expression of Thy-1 on human hematopoietic progenitor cells.

Craig W et al.
J Exp Med.,  (1993)

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Thy-1 expression is linked to functional properties of primitive hematopoietic progenitor cells from human umbilical cord blood.

Mayani H et al.
Blood.,  (1994)

publication_link

 

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