anti-CD94 / KLRD1 antibody [13E3]

Key features and details

  • 产品描述: Mouse Monoclonal antibody [13E3] recognizes CD94 / KLRD1
  • 反应物种: Hu
  • 应用: FACS, WB
  • 宿主: Mouse
  • 克隆: Monoclonal
  • 克隆号: 13E3
  • 同位型: IgG1, kappa
  • 靶点名称: CD94 / KLRD1
  • 抗原物种: Human
  • Brand:
CAT.NO. : ARG57542
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Product Details
概述
产品描述Mouse Monoclonal antibody [13E3] recognizes CD94 / KLRD1
反应物种Hu
应用FACS, WB
宿主Mouse
克隆Monoclonal
克隆号13E3
同位型IgG1, kappa
靶点名称CD94 / KLRD1
抗原物种Human
抗原Recombinant Human CD94 / KLRD1 (aa. 32-179) purified from E. coli
偶联标记Un-conjugated
別名KP43; CD antigen CD94; CD94; Natural killer cells antigen CD94; Killer cell lectin-like receptor subfamily D member 1; NK cell receptor
应用说明
应用建议
应用推荐稀释比
FACS2 - 5 µg/10^6 cells
WB1:1000
应用说明* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
属性
形式Liquid
纯化Purification with Protein A.
缓冲液PBS (pH 7.4), 0.02% Sodium azide and 10% Glycerol.
抗菌剂0.02% Sodium azide
稳定剂10% Glycerol
浓度1 mg/ml
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
数据库连接

GeneID: 3824 Human KLRD1

Swiss-port # Q13241 Human Natural killer cells antigen CD94

基因名称KLRD1
全名killer cell lectin-like receptor subfamily D, member 1
背景介绍Natural killer (NK) cells are a distinct lineage of lymphocytes that mediate cytotoxic activity and secrete cytokines upon immune stimulation. Several genes of the C-type lectin superfamily, including members of the NKG2 family, are expressed by NK cells and may be involved in the regulation of NK cell function. KLRD1 (CD94) is an antigen preferentially expressed on NK cells and is classified as a type II membrane protein because it has an external C terminus. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
生物功能Plays a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T-cells. [UniProt]
预测分子量21 kDa
检测图片 (3)
  • ARG57542 anti-CD94 / KLRD1 antibody [13E3] FACS image

    Flow Cytometry: PBMC cells stained with ARG57542 anti-CD94 / KLRD1 antibody [13E3] at 2 - 5 µg/10^6 cells (red). Secondary Ab: Goat anti-Mouse IgG antibody (Alexa fluor 488). Mouse monoclonal IgG was used as the isotype control (dark gray), cells without incubation with primary and secondary antibody was used as the negative control (light gray).

  • ARG57542 anti-CD94 / KLRD1 antibody [13E3] WB image

    Western blot: 40 µg of K562, MCF7 and A549 cell lysates stained with ARG57542 anti-CD94 / KLRD1 antibody [13E3] at 1:1000 dilution.

  • ARG57542 anti-CD94 / KLRD1 antibody [13E3] WB image

    Western blot: 40 µg of NK-92 cell lysate stained with ARG57542 anti-CD94 / KLRD1 antibody [13E3] at 1:1000 dilution.

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