anti-CD99R antibody [MEM-131]

Key features and details

  • 产品描述: Mouse Monoclonal antibody [MEM-131] recognizes CD99R
  • 反应物种: Hu
  • 应用: FACS, IHC-P, IP, WB
  • 特异性: The clone MEM-131 reacts with CD99R, an epitope restricted to a subset of CD99 molecule expressed on myeloid cells, NK cells and T lymphocytes.HLDA V; WS Code AS S020 HLDA V; WS Code T T-E2.02 HLDA V; WS Code T T-017
  • 宿主: Mouse
  • 克隆: Monoclonal
  • 克隆号: MEM-131
  • 同位型: IgM
  • 靶点名称: CD99R
  • Brand:
CAT.NO. : ARG62958
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Product Details
概述
产品描述Mouse Monoclonal antibody [MEM-131] recognizes CD99R
反应物种Hu
应用FACS, IHC-P, IP, WB
特异性The clone MEM-131 reacts with CD99R, an epitope restricted to a subset of CD99 molecule expressed on myeloid cells, NK cells and T lymphocytes.
HLDA V; WS Code AS S020
HLDA V; WS Code T T-E2.02
HLDA V; WS Code T T-017
宿主Mouse
克隆Monoclonal
克隆号MEM-131
同位型IgM
靶点名称CD99R
抗原物种Human
抗原HPB-ALL human peripheral blood leukemia T-cell line
偶联标记Un-conjugated
別名12E7; CD99 antigen; MIC2X; MIC2Y; CD antigen CD99; MSK5X; Protein MIC2; MIC2; T-cell surface glycoprotein E2; HBA71; E2 antigen
应用说明
应用建议
应用推荐稀释比
FACS1 µg/ml
IHC-P10 µg/ml
IPAssay-dependent
WBAssay-dependent
应用说明WB: Under non-reducing condition.
* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
阳性对照IHC-P: Thymic lymphocytes
属性
形式Liquid
纯化Purified from ascites by precipitation methods.
纯度> 95% (by SDS-PAGE)
缓冲液TBS (pH 8.0) and 15 mM Sodium azide
抗菌剂15 mM Sodium azide
浓度1 mg/ml
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
数据库连接

GeneID: 4267 Human CD99

Swiss-port # P14209 Human CD99 antigen

基因名称CD99
全名CD99 molecule
背景介绍The protein encoded by this gene is a cell surface glycoprotein involved in leukocyte migration, T-cell adhesion, ganglioside GM1 and transmembrane protein transport, and T-cell death by a caspase-independent pathway. In addition, the encoded protein may have the ability to rearrange the actin cytoskeleton and may also act as an oncosuppressor in osteosarcoma. Cyclophilin A binds to CD99 and may act as a signaling regulator of CD99. This gene is found in the pseudoautosomal region of chromosomes X and Y and escapes X-chromosome inactivation. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2013]
生物功能Involved in T-cell adhesion processes and in spontaneous rosette formation with erythrocytes. Plays a role in a late step of leukocyte extravasation helping leukocytes to overcome the endothelial basement membrane. Acts at the same site as, but independently of, PECAM1. Involved in T-cell adhesion processes (By similarity). [UniProt]
研究领域Cancer antibody; Immune System antibody; Signaling Transduction antibody
预测分子量19 kDa
翻译后修饰Extensively O-glycosylated.
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