anti-CD99R antibody [MEM-131] (PE)
![anti-CD99R antibody [MEM-131] (PE)](/upload/image/products/ARG53918_FACS_1_210_205.jpg)
![anti-CD99R antibody [MEM-131] (PE)](/upload/image/products/ARG53918_FACS_1.jpg)
Key features and details
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CAT.NO. : ARG53918
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Product Details
概述
| 产品描述 | PE-conjugated Mouse Monoclonal antibody [MEM-131] recognizes CD99R |
|---|---|
| 反应物种 | Hu |
| 应用 | FACS |
| 特异性 | The clone MEM-131 reacts with CD99R, an epitope restricted to a subset of CD99 molecule expressed on myeloid cells, NK cells and T lymphocytes. HLDA V; WS Code AS S020 HLDA V; WS Code T T-E2.02 HLDA V; WS Code T T-017 |
| 宿主 | Mouse |
| 克隆 | Monoclonal |
| 克隆号 | MEM-131 |
| 同位型 | IgM |
| 靶点名称 | CD99R |
| 抗原物种 | Human |
| 抗原 | HPB-ALL human peripheral blood leukemia T-cell line |
| 偶联标记 | PE |
| 別名 | 12E7; CD99 antigen; MIC2X; MIC2Y; CD antigen CD99; MSK5X; Protein MIC2; MIC2; T-cell surface glycoprotein E2; HBA71; E2 antigen |
应用说明
| 应用建议 |
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|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化说明 | The purified antibody is conjugated with R-Phycoerythrin (PE) under optimum conditions. The conjugate is purified by size-exclusion chromatography and adjusted for direct use. No reconstitution is necessary. |
| 缓冲液 | TBS, 15 mM Sodium azide and 0.2% (w/v) high-grade protease free BSA |
| 抗菌剂 | 15 mM Sodium azide |
| 稳定剂 | 0.2% (w/v) high-grade protease free BSA |
| 存放说明 | Aliquot and store in the dark at 2-8°C. Keep protected from prolonged exposure to light. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | CD99 |
| 全名 | CD99 molecule |
| 背景介绍 | The protein encoded by this gene is a cell surface glycoprotein involved in leukocyte migration, T-cell adhesion, ganglioside GM1 and transmembrane protein transport, and T-cell death by a caspase-independent pathway. In addition, the encoded protein may have the ability to rearrange the actin cytoskeleton and may also act as an oncosuppressor in osteosarcoma. Cyclophilin A binds to CD99 and may act as a signaling regulator of CD99. This gene is found in the pseudoautosomal region of chromosomes X and Y and escapes X-chromosome inactivation. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2013] |
| 生物功能 | Involved in T-cell adhesion processes and in spontaneous rosette formation with erythrocytes. Plays a role in a late step of leukocyte extravasation helping leukocytes to overcome the endothelial basement membrane. Acts at the same site as, but independently of, PECAM1. Involved in T-cell adhesion processes (By similarity). [UniProt] |
| 研究领域 | Cancer antibody; Immune System antibody; Signaling Transduction antibody |
| 预测分子量 | 19 kDa |
| 翻译后修饰 | Extensively O-glycosylated. |
检测图片 (1)
ARG53918 anti-CD99R antibody [MEM-131] (PE) FACS image
Flow Cytometry: Human peripheral blood stained with ARG53918 anti-CD99R antibody [MEM-131] (PE).
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