anti-CDC42 Binding Protein Kinase Beta antibody

Key features and details

  • 产品描述: Mouse Monoclonal antibody recognizes CDC42 Binding Protein Kinase Beta
  • 反应物种: Hu
  • 应用: IHC-P
  • 宿主: Mouse
  • 克隆: Monoclonal
  • 同位型: IgG1
  • 靶点名称: CDC42 Binding Protein Kinase Beta
  • 抗原物种: Human
  • 抗原表位: QRDLEHSLQM EAYERRIRRL EQEKLELSRK LQESTQTVQS LHGSSRALSN SNRDKEIKKL NEEIERLKNK IADSNRLERQ LEDTVALRQE REDSTQRLRG LEKQHRVVRQ EKEELHKQLV EASERLKSQA KELKDAHQQR KLALQEFSEL NERMAELRAQ KQKVSRQLRD KEEEMEVATQ KVDAMRQEMR RAEKLRKELE AQLDDAVAEA SKERKLREHS ENFCKQMESE LEALKVKQGG RGAGATLEHQ QEISKIKSEL EKKVLFYEEE LVRREASHVL EVKNVKKEVH DSESHQLALQ KEILMLKDKL EKSKRERHNE MEEAVGTIKD
  • Brand:
CAT.NO. : ARG44794
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Product Details
概述
产品描述Mouse Monoclonal antibody recognizes CDC42 Binding Protein Kinase Beta
反应物种Hu
应用IHC-P
宿主Mouse
克隆Monoclonal
同位型IgG1
靶点名称CDC42 Binding Protein Kinase Beta
抗原物种Human
抗原表位QRDLEHSLQM EAYERRIRRL EQEKLELSRK LQESTQTVQS LHGSSRALSN SNRDKEIKKL NEEIERLKNK IADSNRLERQ LEDTVALRQE REDSTQRLRG LEKQHRVVRQ EKEELHKQLV EASERLKSQA KELKDAHQQR KLALQEFSEL NERMAELRAQ KQKVSRQLRD KEEEMEVATQ KVDAMRQEMR RAEKLRKELE AQLDDAVAEA SKERKLREHS ENFCKQMESE LEALKVKQGG RGAGATLEHQ QEISKIKSEL EKKVLFYEEE LVRREASHVL EVKNVKKEVH DSESHQLALQ KEILMLKDKL EKSKRERHNE MEEAVGTIKD
偶联标记Un-conjugated
別名CDC42BPB; CDC42 Binding Protein Kinase Beta; KIAA1124; MRCKB; Myotonic Dystrophy Kinase-Related CDC42-Binding Kinase Beta; Myotonic Dystrophy Protein Kinase-Like Beta; Serine/Threonine-Protein Kinase MRCK Beta; DMPK-Like Beta; CDC42BP-Beta; EC 2.7.11.1; MRCK Beta; CDC42-Binding Protein Kinase Beta (DMPK-Like); CDC42 Binding Protein Kinase Beta (DMPK-Like); CDC42-Binding Protein Kinase Beta; EC 2.7.11; CHOCNS
应用说明
应用建议
应用推荐稀释比
IHC-P1:250 - 1:500
应用说明* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
属性
形式Liquid
纯化Protein A purification
缓冲液PBS with 0.09% sodium azide
抗菌剂0.09% sodium azide
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
数据库连接

GeneID: 9578 Human CDC42BPB

Swiss-port # Q9Y5S2 Human Serine/threonine-protein kinase MRCK beta

基因名称CDC42BPB
全名CDC42 Binding Protein Kinase Beta
背景介绍This gene encodes a member of the serine/threonine protein kinase family. The encoded protein contains a Cdc42/Rac-binding p21 binding domain resembling that of PAK kinase. The kinase domain of this protein is most closely related to that of myotonic dystrophy kinase-related ROK. Studies of the similar gene in rat suggested that this kinase may act as a downstream effector of Cdc42 in cytoskeletal reorganization. [provided by RefSeq, Jul 2008]
生物功能In concert with FAM89B/LRAP25 mediates the targeting of LIMK1 to the lamellipodium resulting in its activation and subsequent phosphorylation of CFL1 which is important for lamellipodial F-actin regulation. [Uniprot]
细胞定位Cell junction, Cell membrane, Cell projection, Cytoplasm, Membrane. [Uniprot]
翻译后修饰Methylation, Phosphoprotein. [Uniprot]
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