anti-CDK5RAP3 antibody

Key features and details

  • 产品描述: Rabbit Polyclonal antibody recognizes CDK5RAP3
  • 反应物种: Hu
  • 应用: WB
  • 宿主: Rabbit
  • 克隆: Polyclonal
  • 同位型: IgG
  • 靶点名称: CDK5RAP3
  • 抗原物种: Human
  • 抗原: Recombinant fusion protein corresponding to aa. 1-300 of Human CDK5RAP3 (NP_788276.1).
  • Brand:
CAT.NO. : ARG40022
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Product Details
概述
产品描述Rabbit Polyclonal antibody recognizes CDK5RAP3
反应物种Hu
应用WB
宿主Rabbit
克隆Polyclonal
同位型IgG
靶点名称CDK5RAP3
抗原物种Human
抗原Recombinant fusion protein corresponding to aa. 1-300 of Human CDK5RAP3 (NP_788276.1).
偶联标记Un-conjugated
別名IC53; PP1553; C53; LZAP; Protein HSF-27; OK/SW-cl.114; CDK5 regulatory subunit-associated protein 3; MST016; LXXLL/leucine-zipper-containing ARF-binding protein; CDK5 activator-binding protein C53; HSF-27
应用说明
应用建议
应用推荐稀释比
WB1:500 - 1:2000
应用说明* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
阳性对照U-87 MG
实际分子量65 kDa
属性
形式Liquid
纯化Affinity purified.
缓冲液PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol.
抗菌剂0.02% Sodium azide
稳定剂50% Glycerol
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
数据库连接

GeneID: 80279 Human CDK5RAP3

Swiss-port # Q96JB5 Human CDK5 regulatory subunit-associated protein 3

基因名称CDK5RAP3
全名CDK5 regulatory subunit associated protein 3
背景介绍This gene encodes a protein that has been reported to function in signaling pathways governing transcriptional regulation and cell cycle progression. It may play a role in tumorigenesis and metastasis. A pseudogene of this gene is located on the long arm of chromosome 20. Alternative splicing results in multiple transcript variants that encode different isoforms. [provided by RefSeq, May 2013]
生物功能Potential regulator of CDK5 activity. May be involved in cell proliferation. Regulates CDK5 activity via its interaction with CDK5R1 (By similarity). [UniProt]
细胞定位Nucleus. Cytoplasm. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Note=Colocalizes and associates with microtubules. [UniProt]
预测分子量57 kDa
翻译后修饰May be phosphorylated by CDK5.

Ubiquitinated. Probably triggers proteasomal degradation and is negatively regulated by UFL1.

May be ufmylated.

Cleaved by caspases early during apoptosis, the resulting peptides may play a role in rupture of the nuclear envelope. [UniProt]
检测图片 (1)
  • ARG40022 anti-CDK5RAP3 antibody WB image

    Western blot: 25 µg of U-87 MG cell lysate stained with ARG40022 anti-CDK5RAP3 antibody at 1:1000 dilution.

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