anti-CENTG1 / PIKE antibody
Key features and details
- 产品描述:
- 反应物种:
- 应用:
- 特异性:
- 宿主:
- 克隆:
- 同位型:
- 靶点名称:
- 抗原物种:
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Brand:
Product Details
| 产品描述 | Goat Polyclonal antibody recognizes CENTG1 / PIKE |
|---|---|
| 反应物种 | Hu |
| 应用 | IHC-P, WB |
| 特异性 | This antibody is expected to recognize isoform PIKE-S (NP_055585.1). |
| 宿主 | Goat |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | CENTG1 / PIKE |
| 抗原物种 | Human |
| 抗原 | C-QASLDSIREAVINSQ |
| 偶联标记 | Un-conjugated |
| 別名 | PIKE; GGAP2; AGAP-2; Cnt-g1; Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 2; Phosphatidylinositol 3-kinase enhancer; Centaurin-gamma-1; GTP-binding and GTPase-activating protein 2; CENTG1 |
| 应用建议 |
| ||||||
|---|---|---|---|---|---|---|---|
| 应用说明 | WB: Recommend incubate at RT for 1h. IHC-P: Antigen Retrieval: Steam tissue section in Citrate buffer (pH 6.0). * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
| 形式 | Liquid |
|---|---|
| 纯化 | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| 缓冲液 | Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 0.5% BSA |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
| 数据库连接 | Swiss-port # Q99490 Human Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 2 |
|---|---|
| 背景介绍 | The protein encoded by this gene belongs to the centaurin gamma-like family. It mediates anti-apoptotic effects of nerve growth factor by activating nuclear phosphoinositide 3-kinase. It is overexpressed in cancer cells, and promotes cancer cell invasion. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Aug 2011] |
| 研究领域 | Gene Regulation antibody; Signaling Transduction antibody |
| 预测分子量 | 125 kDa |
| 翻译后修饰 | Isoform PIKE-A is phosphorylated at Tyr-682 and Tyr-774 by FYN, preventing its apoptotic cleavage. |
ARG64931 anti-CENTG1 / PIKE antibody WB image
Western Blot: Human Amygdala lysate (35 µg protein in RIPA buffer) stained with ARG64931 anti-CENTG1 / PIKE antibody at 0.3 µg/ml dilution.
ARG64931 anti-CENTG1 / PIKE antibody IHC-P image
Immunohistochemistry: Paraffin-embedded Human thyroid tissue. Antigen Retrieval: Steam tissue section in Citrate buffer (pH 6.0). The tissue section was stained with ARG64931 anti-CENTG1 / PIKE antibody at 3.75 µg/ml dilution followed by AP-staining.
ARG64931 anti-CENTG1 / PIKE antibody IHC-P image
Immunohistochemistry: Paraffin-embedded Human kidney tissue. Antigen Retrieval: Steam tissue section in Citrate buffer (pH 6.0). The tissue section was stained with ARG64931 anti-CENTG1 / PIKE antibody at 3.75 µg/ml dilution followed by AP-staining.
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