anti-ChAT antibody
Key features and details
- 产品描述:
- 反应物种:
- 应用:
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- 克隆:
- 同位型:
- 靶点名称:
- 抗原物种:
- 抗原:
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Brand:
CAT.NO. : ARG52243
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Product Details
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes ChAT |
|---|---|
| 反应物种 | Ms, Rat, NHuPrm |
| 应用 | IHC, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | ChAT |
| 抗原物种 | Human |
| 抗原 | Native choline acetyltransferase purifed from human placenta |
| 偶联标记 | Un-conjugated |
| 別名 | CMS1A; Choline acetylase; CHOACTase; CHOACTASE; EC 2.3.1.6; CMS6; Choline O-acetyltransferase; ChAT; CMS1A2 |
应用说明
| 应用建议 |
| ||||||
|---|---|---|---|---|---|---|---|
| 应用说明 | Specific for the ~ 68/70 k choline acetyltransferase protein * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Neat serum |
| 缓冲液 | Neat serum |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | CHAT |
| 全名 | choline O-acetyltransferase |
| 背景介绍 | Choline acetyltransferase is a neuronal enzyme which catalyzes the reaction between Acetyl CoA and choline resulting in the formation of acetylcholine. It is therefore found primarily in cholinergic neurons making it a valuable marker for diseases associated with decreased cholinergic function such as Schizophrenia, Alzheimer disease (AD) and Down syndrome (Holt et al. 1999). Decreased choline acetyltransferase activity in particular has been shown in Schizophrenic subjects (Karson et al 1993). It has furthermore been demonstrated that in patients with AD, there are significantly lower levels of cortical ChAT that correlate with severity of the disease as measured by loss of neuropsychological function (Baskin et al. 1999). |
| 研究领域 | Neuroscience antibody |
| 预测分子量 | 83 kDa |
检测图片 (1)
ARG52243 anti-ChAT antibody WB image
Western blot: rat brain lysate ARG52243 anti-ChAT antibody showing specific immunolabeling of the ~68/70k ChAT
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