anti-CHD4 antibody
Key features and details
- 产品描述:
- 反应物种:
- 应用:
- 宿主:
- 克隆:
- 同位型:
- 靶点名称:
- 抗原物种:
- 抗原:
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Brand:
CAT.NO. : ARG41825
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Product Details
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes CHD4 |
|---|---|
| 反应物种 | Hu |
| 应用 | FACS, ICC/IF, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | CHD4 |
| 抗原物种 | Human |
| 抗原 | Synthetic peptide of Human CHD4. |
| 偶联标记 | Un-conjugated |
| 別名 | Chromodomain-helicase-DNA-binding protein 4; Mi-2b; EC 3.6.4.12; Mi-2 autoantigen 218 kDa protein; CHD-4; Mi2-beta; ATP-dependent helicase CHD4; Mi2-BETA |
应用说明
| 应用建议 |
| ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||
| 阳性对照 | 293T |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified. |
| 缓冲液 | PBS (pH 7.4), 150 mM NaCl, 0.02% Sodium azide and 50% Glycerol. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 50% Glycerol |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | Swiss-port # Q14839 Human Chromodomain-helicase-DNA-binding protein 4 |
|---|---|
| 基因名称 | CHD4 |
| 全名 | chromodomain helicase DNA binding protein 4 |
| 背景介绍 | The product of this gene belongs to the SNF2/RAD54 helicase family. It represents the main component of the nucleosome remodeling and deacetylase complex and plays an important role in epigenetic transcriptional repression. Patients with dermatomyositis develop antibodies against this protein. Somatic mutations in this gene are associated with serous endometrial tumors. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2014] |
| 生物功能 | Component of the histone deacetylase NuRD complex which participates in the remodeling of chromatin by deacetylating histones. [UniProt] |
| 细胞定位 | Nucleus. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Note=Associates with centrosomes in interphase. [UniProt] |
| 预测分子量 | 218 kDa |
检测图片 (1)
ARG41825 anti-CHD4 antibody WB image
Western blot: 293T cell lysate stained with ARG41825 anti-CHD4 antibody.
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