anti-CHML / REP2 antibody
Key features and details
- 产品描述:
- 反应物种:
- 应用:
- 宿主:
- 克隆:
- 同位型:
- 靶点名称:
- 抗原物种:
- 抗原:
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Brand:
CAT.NO. : ARG42536
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Product Details
概述
| 产品描述 | Goat Polyclonal antibody recognizes CHML / REP2 |
|---|---|
| 反应物种 | Hu, Ms, Rat, Dog, Mk |
| 应用 | WB |
| 宿主 | Goat |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | CHML / REP2 |
| 抗原物种 | Human |
| 抗原 | Purified recombinant peptide within aa. 617 to the C-terminus of Human CHML / REP2. |
| 偶联标记 | Un-conjugated |
| 別名 | Rab proteins geranylgeranyltransferase component A 2; Choroideremia-like protein; REP2; Rab escort protein 2; REP-2 |
应用说明
| 应用建议 |
| ||||
|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
| 阳性对照 | LS174T and HeLa | ||||
| 实际分子量 | ~ 80 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purification with immunogen. |
| 缓冲液 | PBS, 0.05% Sodium azide and 20% Glycerol. |
| 抗菌剂 | 0.05% Sodium azide |
| 稳定剂 | 20% Glycerol |
| 浓度 | 3 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | Swiss-port # P26374 Human Rab proteins geranylgeranyltransferase component A 2 Swiss-port # Q9QZD5 Mouse Rab proteins geranylgeranyltransferase component A 2 |
|---|---|
| 基因名称 | CHML |
| 全名 | choroideremia-like (Rab escort protein 2) |
| 背景介绍 | The product of the CHML gene supports geranylgeranylation of most Rab proteins and may substitute for REP-1 in tissues other than retina. CHML is localized close to the gene for Usher syndrome type II. [provided by RefSeq, Jul 2008] |
| 生物功能 | Substrate-binding subunit (component A) of the Rab geranylgeranyltransferase (GGTase) complex. Binds unprenylated Rab proteins and presents the substrate peptide to the catalytic component B. The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane. Less effective than CHM in supporting prenylation of Rab3 family. [UniProt] |
| 细胞定位 | Cytoplasm, cytosol. [UniProt] |
| 预测分子量 | 74 kDa |
检测图片 (1)
ARG42536 anti-CHML / REP2 antibody WB image
Western blot: 50 µg of LS174T and HeLa cell lysates stained with ARG42536 anti-CHML / REP2 antibody at 1:1000 dilution.
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