anti-CHRNA1 / Nicotinic Acetylcholine R alpha 1 antibody
Key features and details
- 产品描述:
- 反应物种:
- 预测物种:
- 应用:
- 宿主:
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- 同位型:
- 靶点名称:
- 抗原物种:
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Brand:
CAT.NO. : ARG58430
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Product Details
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes CHRNA1 / Nicotinic Acetylcholine R alpha 1 |
|---|---|
| 反应物种 | Rat |
| 预测物种 | Hm |
| 应用 | WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | CHRNA1 / Nicotinic Acetylcholine R alpha 1 |
| 抗原物种 | Human |
| 抗原 | Synthetic peptide corresponding to aa. 22-36 of Human Nicotinic Acetylcholine Receptor alpha 1 (EHETRLVAKLFKDYS). Identical to the related Rat sequence, different from the related Mouse sequence by one amino acid. |
| 偶联标记 | Un-conjugated |
| 別名 | CMS1A; FCCMS; CMS1B; SCCMS; CMS2A; Acetylcholine receptor subunit alpha; CHRNA; ACHRA; ACHRD |
应用说明
| 应用建议 |
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|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purification with immunogen. |
| 缓冲液 | 0.9% NaCl, 0.2% Na2HPO4, 0.05% Thimerosal, 0.05% Sodium azide and 5% BSA. |
| 抗菌剂 | 0.05% Thimerosal and 0.05% Sodium azide |
| 稳定剂 | 5% BSA |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | Swiss-port # P25108 Rat Acetylcholine receptor subunit alpha |
|---|---|
| 基因名称 | CHRNA1 |
| 全名 | cholinergic receptor, nicotinic, alpha 1 (muscle) |
| 背景介绍 | The muscle acetylcholine receptor consiststs of 5 subunits of 4 different types: 2 alpha subunits and 1 each of the beta, gamma, and delta subunits. This gene encodes an alpha subunit that plays a role in acetlycholine binding/channel gating. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Nov 2012] |
| 生物功能 | After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. [UniProt] |
| 细胞定位 | Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein. [UniProt] |
| 预测分子量 | 55 kDa |
检测图片 (1)
ARG58430 anti-CHRNA1 / Nicotinic Acetylcholine R alpha 1 antibody WB image
Western blot: Rat skeletal muscle lysate stained with ARG58430 anti-CHRNA1 / Nicotinic Acetylcholine R alpha 1 antibody.
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