anti-CHRNA4 antibody

Key features and details

  • 产品描述: Goat Polyclonal antibody recognizes CHRNA4
  • 反应物种: Hu, Rat
  • 预测物种: Ms, Cow, Dog
  • 应用: WB
  • 特异性: This antibody is expected NOT to cross-react with the similar alpha 2 subunit.
  • 宿主: Goat
  • 克隆: Polyclonal
  • 同位型: IgG
  • 靶点名称: CHRNA4
  • Brand:
CAT.NO. : ARG64681
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Product Details
概述
产品描述Goat Polyclonal antibody recognizes CHRNA4
反应物种Hu, Rat
预测物种Ms, Cow, Dog
应用WB
特异性This antibody is expected NOT to cross-react with the similar alpha 2 subunit.
宿主Goat
克隆Polyclonal
同位型IgG
靶点名称CHRNA4
抗原物种Human
抗原C-HVETRAHAEERLLKK
偶联标记Un-conjugated
別名Neuronal acetylcholine receptor subunit alpha-4; NACRA4; NACHRA4; EBN; BFNC; EBN1; NACHR
应用说明
应用建议
应用推荐稀释比
WB1 - 3 µg/ml
应用说明WB: Recommend incubate at RT for 1h.
* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
属性
形式Liquid
纯化Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
缓冲液Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA
抗菌剂0.02% Sodium azide
稳定剂0.5% BSA
浓度0.5 mg/ml
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
数据库连接

GeneID: 1137 Human CHRNA4

GeneID: 25590 Rat CHRNA4

Swiss-port # P09483 Rat Neuronal acetylcholine receptor subunit alpha-4

Swiss-port # P43681 Human Neuronal acetylcholine receptor subunit alpha-4

背景介绍This gene encodes a nicotinic acetylcholine receptor, which belongs to a superfamily of ligand-gated ion channels that play a role in fast signal transmission at synapses. These pentameric receptors can bind acetylcholine, which causes an extensive change in conformation that leads to the opening of an ion-conducting channel across the plasma membrane. This protein is an integral membrane receptor subunit that can interact with either nAChR beta-2 or nAChR beta-4 to form a functional receptor. Mutations in this gene cause nocturnal frontal lobe epilepsy type 1. Polymorphisms in this gene that provide protection against nicotine addiction have been described. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2012]
研究领域Cancer antibody; Metabolism antibody; Neuroscience antibody
预测分子量70 kDa
检测图片 (1)
  • ARG64681 anti-CHRNA4antibody WB image

    Western Blot: Rat Brain lysate (35 µg protein in RIPA buffer) stained with ARG64681 anti-CHRNA4 (aa29-43) antibody at 0.3 µg/ml dilution.

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