anti-CIDE B antibody
CAT.NO. : ARG54338
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概述
| 产品描述 | Rabbit Polyclonal antibody recognizes CIDE B |
|---|---|
| 反应物种 | Ms |
| 应用 | WB |
| 特异性 | This antibody recognizes mouse CIDE-B (25kDa) and does not cross-react with CIDE-A. |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | CIDE B |
| 抗原物种 | Mouse |
| 抗原 | Peptide corresponding to aa 204-219 of mouse CIDE-B (accession no. AF041377). |
| 偶联标记 | Un-conjugated |
| 別名 | Cell death-inducing DFFA-like effector B; Cell death activator CIDE-B |
应用说明
| 应用建议 |
| ||||
|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
| 阳性对照 | Mouse liver |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Immunoaffinity chroma-tography |
| 缓冲液 | PBS (pH 7.4) and 0.02% Sodium azide |
| 抗菌剂 | 0.02% Sodium azide |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | Cideb |
| 全名 | cell death-inducing DNA fragmentation factor, alpha subunit-like effector B |
| 背景介绍 | DFF45-related proteins CIDE-A and CIDE-B have recently been identified. CIDE contains a new type of domain termed CIDE-N, which has high homology with the regulatory domains of DFF45/ICAD and DFF40/CAD. Expression of CIDE-B induces apoptosis, which is inhibited by DFF45. CIDE-B is a DFF45-inhibitable effector that promotes cell death and DNA fragmentation. CIDE-B is expressed mainly in liver and at lower levels in spleen, kidney, peripheral blood lymphocytes, and bone marrow. |
| 生物功能 | Activates apoptosis. [UniProt] |
| 研究领域 | Cell Biology and Cellular Response antibody; Cell Death antibody; Gene Regulation antibody; Metabolism antibody |
| 预测分子量 | 25 kDa |
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