anti-CILP antibody
Key features and details
- 产品描述:
- 反应物种:
- 预测物种:
- 应用:
- 宿主:
- 克隆:
- 同位型:
- 靶点名称:
- 抗原物种:
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Brand:
CAT.NO. : ARG64007
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Product Details
概述
| 产品描述 | Goat Polyclonal antibody recognizes CILP |
|---|---|
| 反应物种 | Rat |
| 预测物种 | Hu, Ms, Dog |
| 应用 | WB |
| 宿主 | Goat |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | CILP |
| 抗原物种 | Human |
| 抗原 | C-NYRRTDHEDPRVK |
| 偶联标记 | Un-conjugated |
| 別名 | Cartilage intermediate layer protein 1; Cartilage intermediate-layer protein; CILP-1; HsT18872 |
应用说明
| 应用建议 |
| ||||
|---|---|---|---|---|---|
| 应用说明 | WB: Recommend incubate at RT for 1h. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| 缓冲液 | Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 0.5% BSA |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 背景介绍 | Major alterations in the composition of the cartilage extracellular matrix occur in joint disease, such as osteoarthrosis. This gene encodes the cartilage intermediate layer protein (CILP), which increases in early osteoarthrosis cartilage. The encoded protein was thought to encode a protein precursor for two different proteins; an N-terminal CILP and a C-terminal homolog of NTPPHase, however, later studies identified no nucleotide pyrophosphatase phosphodiesterase (NPP) activity. The full-length and the N-terminal domain of this protein was shown to function as an IGF-1 antagonist. An allelic variant of this gene has been associated with lumbar disc disease. [provided by RefSeq, Sep 2010] |
|---|---|
| 研究领域 | Immune System antibody; Signaling Transduction antibody |
| 预测分子量 | 133 kDa |
| 翻译后修饰 | Cleaved into 2 chains possibly by a furin-like protease upon or preceding secretion. |
检测图片 (1)
ARG64007 anti-CILP antibody WB image
Western Blot: rat spinal cord lysate (35 µg protein in RIPA buffer) stained with ARG64007 anti-CILP antibody at 0.03 µg/ml dilution.
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