anti-CISD1 / mitoNEET antibody [1A8]

CAT.NO. : ARG57013

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Size:

50 μl

*产品价格可能会有所调整，请以品牌方官网实时更新的价格为准，以确保准确性。

Product Details

概述

产品描述	Mouse Monoclonal antibody [1A8] recognizes CISD1 / mitoNEET
反应物种	Hu
应用	FACS, WB
宿主	Mouse
克隆	Monoclonal
克隆号	1A8
同位型	IgG1, kappa
靶点名称	CISD1 / mitoNEET
抗原物种	Human
抗原	Recombinant fragment around aa. 32-108 of Human CISD1 / mitoNEET.
偶联标记	Un-conjugated
別名	MDS029; mitoNEET; C10orf70; CDGSH iron-sulfur domain-containing protein 1; MitoNEET; ZCD1

应用说明

应用建议

应用	推荐稀释比
FACS	Assay-dependent
WB	1:1000

应用说明

* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

属性

形式	Liquid
纯化	Purification with Protein A.
缓冲液	PBS (pH 7.4), 0.02% Sodium azide and 10% Glycerol.
抗菌剂	0.02% Sodium azide
稳定剂	10% Glycerol
浓度	1 mg/ml
存放说明	For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项	For laboratory research only, not for drug, diagnostic or other use.

生物信息

数据库连接	GeneID: 55847 Human CISD1 Swiss-port # Q9NZ45 Human CDGSH iron-sulfur domain-containing protein 1
基因名称	CISD1
全名	CDGSH iron sulfur domain 1
背景介绍	This gene encodes a protein with a CDGSH iron-sulfur domain and has been shown to bind a redox-active [2Fe-2S] cluster. The encoded protein has been localized to the outer membrane of mitochondria and is thought to play a role in regulation of oxidation. Genes encoding similar proteins are located on chromosomes 4 and 17, and a pseudogene of this gene is located on chromosome 2. [provided by RefSeq, Feb 2012]
生物功能	Plays a key role in regulating maximal capacity for electron transport and oxidative phosphorylation (By similarity). May be involved in Fe-S cluster shuttling and/or in redox reactions. [UniProt]
预测分子量	12 kDa
翻译后修饰	Ubiquitinated by PRKN during mitophagy, leading to its degradation and enhancement of mitophagy. Deubiquitinated by USP30.

检测图片 (3)

ARG57013 anti-CISD1 / mitoNEET antibody [1A8] FACS image
Flow Cytometry: THP-1 cell line stained with ARG57013 anti-CISD1 / mitoNEET antibody [1A8] at 2-5 µg for 1x10^6 cells (red line). Secondary antibody: Goat anti-Mouse IgG Alexa fluor 488 conjugate. Isotype control antibody was Mouse IgG (black line).
ARG57013 anti-CISD1 / mitoNEET antibody [1A8] WB image
Western blot: 40 µg of Mouse liver lysate stained with ARG57013 anti-CISD1 / mitoNEET antibody [1A8] at 1:1000.
ARG57013 anti-CISD1 / mitoNEET antibody [1A8] WB image
Western blot: 40 µg of 1) K562 cell lysate, 2) MCF7 cell lysate stained with ARG57013 anti-CISD1 / mitoNEET antibody [1A8] at 1:1000.

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