anti-CISD2 antibody

Key features and details

  • 产品描述: Rabbit Polyclonal antibody recognizes CISD2
  • 反应物种: Hu, Ms, Rat
  • 应用: IHC-P, WB
  • 宿主: Rabbit
  • 克隆: Polyclonal
  • 同位型: IgG
  • 靶点名称: CISD2
  • 抗原物种: Human
  • 抗原: Recombinant protein of Human CISD2.
  • Brand:
CAT.NO. : ARG57426
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Product Details
概述
产品描述Rabbit Polyclonal antibody recognizes CISD2
反应物种Hu, Ms, Rat
应用IHC-P, WB
宿主Rabbit
克隆Polyclonal
同位型IgG
靶点名称CISD2
抗原物种Human
抗原Recombinant protein of Human CISD2.
偶联标记Un-conjugated
別名MitoNEET-related 1 protein; Miner1; ERIS; Endoplasmic reticulum intermembrane small protein; CDGSH iron-sulfur domain-containing protein 2; Nutrient-deprivation autophagy factor-1; WFS2; NAF-1; ZCD2
应用说明
应用建议
应用推荐稀释比
IHC-P1:50 - 1:200
WB1:500 - 1:2000
应用说明* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
阳性对照A549
属性
形式Liquid
纯化Affinity purification with immunogen.
缓冲液PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol.
抗菌剂0.02% Sodium azide
稳定剂50% Glycerol
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
数据库连接

GeneID: 493856 Human CISD2

GeneID: 67006 Mouse CISD2

Swiss-port # Q8N5K1 Human CDGSH iron-sulfur domain-containing protein 2

Swiss-port # Q9CQB5 Mouse CDGSH iron-sulfur domain-containing protein 2

基因名称CISD2
全名CDGSH iron sulfur domain 2
背景介绍The protein encoded by this gene is a zinc finger protein that localizes to the endoplasmic reticulum. The encoded protein binds an iron/sulfur cluster and may be involved in calcium homeostasis. Defects in this gene are a cause of Wolfram syndrome 2. [provided by RefSeq, Mar 2011]
生物功能Regulator of autophagy that contributes to antagonize BECN1-mediated cellular autophagy at the endoplasmic reticulum. Participates in the interaction of BCL2 with BECN1 and is required for BCL2-mediated depression of endoplasmic reticulum Ca(2+) stores during autophagy. Contributes to BIK-initiated autophagy, while it is not involved in BIK-dependent activation of caspases. Involved in life span control, probably via its function as regulator of autophagy. [UniProt]
预测分子量15 kDa
检测图片 (1)
  • ARG57426 anti-CISD2 antibody WB image

    Western blot: A549 cell lysate stained with ARG57426 anti-CISD2 antibody.

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