anti-CLEC2 / CLEC1B antibody [17D9]
![anti-CLEC2 / CLEC1B antibody [17D9]](/upload/image/20241105/8415bc38bc270b898ee2a90369a6c7fb.jpg)
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- 反应物种:
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- 克隆:
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- 抗原物种:
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CAT.NO. : ARG22588
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Product Details
概述
| 产品描述 | Rat Monoclonal antibody [17D9] recognizes CLEC2 / CLEC1B This antibody recognizes mouse C-type lectin domain family 1 member B, also known as CLEC2 or CLEC1B. CLEC2 acts as a receptor for rhodocytin, a platelet-aggregating protein found in snake venom. CLEC2 expression is not restricted to platelets and also acts as an activation receptor on neutrophils. |
|---|---|
| 反应物种 | Ms |
| 应用 | FACS, WB |
| 宿主 | Rat |
| 克隆 | Monoclonal |
| 克隆号 | 17D9 |
| 同位型 | IgG2b |
| 靶点名称 | CLEC2 / CLEC1B |
| 抗原物种 | Mouse |
| 抗原 | RBL-2H3 cells stably expressing HA-tagged mouse CLEC2. |
| 偶联标记 | Un-conjugated |
| 別名 | CLEC2; C-type lectin domain family 1 member B; CLEC2B; PRO1384; C-type lectin-like receptor 2; CLEC-2; 1810061I13Rik; QDED721 |
应用说明
| 应用建议 |
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|---|---|---|---|---|---|---|---|
| 应用说明 | FACS: Use 10ul of the suggested working dilution to label 10^6 cells in 100ul. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purification with Protein G. |
| 缓冲液 | PBS and 0.09% Sodium azide |
| 抗菌剂 | 0.09% Sodium azide |
| 浓度 | 1 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | Swiss-port # Q9JL99 Mouse C-type lectin domain family 1 member B |
|---|---|
| 基因名称 | Clec1b |
| 全名 | C-type lectin domain family 1, member b |
| 背景介绍 | Natural killer (NK) cells express multiple calcium-dependent (C-type) lectin-like receptors, such as CD94 (KLRD1; MIM 602894) and NKG2D (KLRC4; MIM 602893), that interact with major histocompatibility complex class I molecules and either inhibit or activate cytotoxicity and cytokine secretion. CLEC2 is a C-type lectin-like receptor expressed in myeloid cells and NK cells (Colonna et al., 2000 [PubMed 10671229]).[supplied by OMIM, Jan 2011] |
| 预测分子量 | 27 kDa |
| 翻译后修饰 | Glycosylated. Phosphorylated on tyrosine residue in response to rhodocytin binding. |
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