anti-CLEC9A antibody [8F9] (PE)

Key features and details

  • 产品描述: PE-conjugated Mouse Monoclonal antibody [8F9] recognizes CLEC9A
  • 反应物种: Hu
  • 应用: FACS
  • 特异性: The mouse monoclonal antibody 8F9 recognizes an extracellular epitope of CD370 / CLEC9A (DNGR1), a type II transmembrane protein functioning as an endocytic receptor on BDCA31+ dendritic cells and on a subset of CD14+ CD16- monocytes.
  • 宿主: Mouse
  • 克隆: Monoclonal
  • 克隆号: 8F9
  • 同位型: IgG2a
  • 靶点名称: CLEC9A
  • Brand:
CAT.NO. : ARG42357
US$ Please choose
US$ Please choose
Size:
Trail, Bulk size or Custom requests Please contact us
*产品价格可能会有所调整,请以品牌方官网实时更新的价格为准,以确保准确性。
Product Details
概述
产品描述PE-conjugated Mouse Monoclonal antibody [8F9] recognizes CLEC9A
反应物种Hu
应用FACS
特异性The mouse monoclonal antibody 8F9 recognizes an extracellular epitope of CD370 / CLEC9A (DNGR1), a type II transmembrane protein functioning as an endocytic receptor on BDCA31+ dendritic cells and on a subset of CD14+ CD16- monocytes.
宿主Mouse
克隆Monoclonal
克隆号8F9
同位型IgG2a
靶点名称CLEC9A
抗原物种Human
抗原RBL-2H3 cells expressing Human CLEC9A fused to an HA epitope.
偶联标记PE
別名UNQ9341; C-type lectin domain family 9 member A; CD370; DNGR-1; DNGR1
应用说明
应用建议
应用推荐稀释比
FACS10 µl / 100 µl of whole blood or 10^6 cells
应用说明* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
属性
形式Liquid
纯化Purified
缓冲液PBS and 15 mM Sodium azide.
抗菌剂15 mM Sodium azide
存放说明Aliquot and store in the dark at 2-8°C. Keep protected from prolonged exposure to light. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
数据库连接

GeneID: 283420 Human CLEC9A

Swiss-port # Q6UXN8 Human C-type lectin domain family 9 member A

基因名称CLEC9A
全名C-type lectin domain family 9, member A
背景介绍CLEC9A is a group V C-type lectin-like receptor (CTLR) that functions as an activation receptor and is expressed on myeloid lineage cells (Huysamen et al., 2008 [PubMed 18408006]).[supplied by OMIM, Aug 2008]
生物功能Functions as an endocytic receptor on a small subset of myeloid cells specialized for the uptake and processing of material from dead cells. Recognizes filamentous form of actin in association with particular actin-binding domains of cytoskeletal proteins, including spectrin, exposed when cell membranes are damaged, and mediate the cross-presentation of dead-cell associated antigens in a Syk-dependent manner. [UniProt]
细胞定位Membrane; Single-pass type II membrane protein. [UniProt]
预测分子量27 kDa
翻译后修饰N-glycosylated. [UniProt]
检测图片 (3)
  • ARG42357 anti-CLEC9A antibody [8F9] (PE) FACS image

    Flow Cytometry: Human peripheral whole blood stained with ARG42357 anti-CLEC9A antibody [8F9] (PE) at 10 µl / 100 µl of peripheral whole blood.

  • ARG42357 anti-CLEC9A antibody [8F9] (PE) FACS image

    Flow Cytometry: Human peripheral blood mononuclear cells stained with ARG42357 anti-CLEC9A antibody [8F9] (PE) at 10 µl / 100 µl of peripheral whole blood and ARG53938 anti-HLA DR antibody [MEM-12] (APC) at 10 µl / 100 µl of peripheral whole blood.

  • ARG42357 anti-CLEC9A antibody [8F9] (PE) FACS image

    Flow Cytometry: Separation of Human CD370 positive HLA-DR positive cells (red-filled) from CD370 negative HLA-DR negative cells (black-dashed). Human peripheral whole blood stained with ARG42357 anti-CLEC9A antibody [8F9] (PE) at 10 µl / 100 µl of peripheral whole blood.

New Products
Get in touch with AREX
Name:*
Tel/Phone:*
Company:*
Email:*
Inquiry:
Captcha*
Submitting your email information means that you are willing to receive email information from AREX regarding technology, applications, products, and events. By clicking on the 'unsubscribe' button in the email or by contacting info@arexbio.com You can unsubscribe at any time by sending an email. Regarding your data usage information, please refer to our privacy policy.
© AREX 2024. All Rights Reserved. | 浙ICP备2024113709号-3 Sitemap