anti-CLEC9A antibody [8F9] (PE)

产品描述: PE-conjugated Mouse Monoclonal antibody [8F9] recognizes CLEC9A
反应物种: Hu
应用: FACS
特异性: The mouse monoclonal antibody 8F9 recognizes an extracellular epitope of CD370 / CLEC9A (DNGR1), a type II transmembrane protein functioning as an endocytic receptor on BDCA31+ dendritic cells and on a subset of CD14+ CD16- monocytes.
宿主: Mouse
克隆: Monoclonal
克隆号: 8F9
同位型: IgG2a
靶点名称: CLEC9A

CAT.NO. : ARG42357

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Size:

50 tests

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Product Details

概述

产品描述	PE-conjugated Mouse Monoclonal antibody [8F9] recognizes CLEC9A
反应物种	Hu
应用	FACS
特异性	The mouse monoclonal antibody 8F9 recognizes an extracellular epitope of CD370 / CLEC9A (DNGR1), a type II transmembrane protein functioning as an endocytic receptor on BDCA31+ dendritic cells and on a subset of CD14+ CD16- monocytes.
宿主	Mouse
克隆	Monoclonal
克隆号	8F9
同位型	IgG2a
靶点名称	CLEC9A
抗原物种	Human
抗原	RBL-2H3 cells expressing Human CLEC9A fused to an HA epitope.
偶联标记	PE
別名	UNQ9341; C-type lectin domain family 9 member A; CD370; DNGR-1; DNGR1

应用说明

应用建议

应用	推荐稀释比
FACS	10 µl / 100 µl of whole blood or 10^6 cells

应用说明

* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

属性

形式	Liquid
纯化	Purified
缓冲液	PBS and 15 mM Sodium azide.
抗菌剂	15 mM Sodium azide
存放说明	Aliquot and store in the dark at 2-8°C. Keep protected from prolonged exposure to light. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项	For laboratory research only, not for drug, diagnostic or other use.

生物信息

数据库连接	GeneID: 283420 Human CLEC9A Swiss-port # Q6UXN8 Human C-type lectin domain family 9 member A
基因名称	CLEC9A
全名	C-type lectin domain family 9, member A
背景介绍	CLEC9A is a group V C-type lectin-like receptor (CTLR) that functions as an activation receptor and is expressed on myeloid lineage cells (Huysamen et al., 2008 [PubMed 18408006]).[supplied by OMIM, Aug 2008]
生物功能	Functions as an endocytic receptor on a small subset of myeloid cells specialized for the uptake and processing of material from dead cells. Recognizes filamentous form of actin in association with particular actin-binding domains of cytoskeletal proteins, including spectrin, exposed when cell membranes are damaged, and mediate the cross-presentation of dead-cell associated antigens in a Syk-dependent manner. [UniProt]
细胞定位	Membrane; Single-pass type II membrane protein. [UniProt]
预测分子量	27 kDa
翻译后修饰	N-glycosylated. [UniProt]

检测图片 (3)

ARG42357 anti-CLEC9A antibody [8F9] (PE) FACS image
Flow Cytometry: Human peripheral whole blood stained with ARG42357 anti-CLEC9A antibody [8F9] (PE) at 10 µl / 100 µl of peripheral whole blood.
ARG42357 anti-CLEC9A antibody [8F9] (PE) FACS image
Flow Cytometry: Human peripheral blood mononuclear cells stained with ARG42357 anti-CLEC9A antibody [8F9] (PE) at 10 µl / 100 µl of peripheral whole blood and ARG53938 anti-HLA DR antibody [MEM-12] (APC) at 10 µl / 100 µl of peripheral whole blood.
ARG42357 anti-CLEC9A antibody [8F9] (PE) FACS image
Flow Cytometry: Separation of Human CD370 positive HLA-DR positive cells (red-filled) from CD370 negative HLA-DR negative cells (black-dashed). Human peripheral whole blood stained with ARG42357 anti-CLEC9A antibody [8F9] (PE) at 10 µl / 100 µl of peripheral whole blood.

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