anti-CNPase antibody [11-5B]

Key features and details

  • 产品描述: Mouse Monoclonal antibody [11-5B] recognizes CNPase
  • 反应物种: Hu, Ms, Rat, Dog, R. Mk
  • 预测物种: Bov, Pig, Rb, Sheep
  • 不反应物种: Chk, Gpig
  • 应用: Conj, Dot, ELISA, FACS, ICC/IF, IHC-Fr, IHC-P, IP, WB
  • 宿主: Mouse
  • 克隆: Monoclonal
  • 克隆号: 11-5B
  • 同位型: IgG1
  • Brand:
CAT.NO. : ARG62449
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Product Details
概述
产品描述Mouse Monoclonal antibody [11-5B] recognizes CNPase
反应物种Hu, Ms, Rat, Dog, R. Mk
预测物种Bov, Pig, Rb, Sheep
不反应物种Chk, Gpig
应用Conj, Dot, ELISA, FACS, ICC/IF, IHC-Fr, IHC-P, IP, WB
宿主Mouse
克隆Monoclonal
克隆号11-5B
同位型IgG1
靶点名称CNPase
抗原物种Human
抗原Purified human 2’-3’-cyclic nucleotide 3’-phosphodiesterase (CNPase)
偶联标记Un-conjugated
別名CNPase; 2',3'-cyclic-nucleotide 3'-phosphodiesterase; CNP1; CNP; EC 3.1.4.37
应用说明
应用建议
应用推荐稀释比
ConjAssay-dependent
DotAssay-dependent
ELISAAssay-dependent
FACSAssay-dependent
ICC/IFAssay-dependent
IHC-FrAssay-dependent
IHC-P1:400
IPAssay-dependent
WBAssay-dependent
应用说明* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
阳性对照Brain
属性
形式Liquid
纯化Purified Antibody
缓冲液1X PBS and 0.1% Sodium azide
抗菌剂0.1% Sodium azide
浓度0.2 mg/ml
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
数据库连接

GeneID: 1267 Human CNP

GeneID: 12799 Mouse CNP

GeneID: 25275 Rat CNP

基因名称CNP
全名2',3'-cyclic nucleotide 3' phosphodiesterase
生物功能May participate in RNA metabolism in the myelinating cell, CNP is the third most abundant protein in central nervous system myelin. [UniProt]
研究领域Controls and Markers antibody; Neuroscience antibody
预测分子量48 kDa
参考文献

克隆号文献

Role of 2',3'-cyclic nucleotide 3'-phosphodiesterase in the renal 2',3'-cAMP-adenosine pathway.

Jackson EK et al.
Am J Physiol Renal Physiol.,  (2014)

publication_link

 

hr_line

Fluorescence-activated sorting of fixed nuclei: a general method for studying nuclei from specific cell populations that preserves post-translational modifications.

FACS / Mouse

Marion-Poll L et al.
Eur J Neurosci.,  (2014)

publication_link

 

hr_line

Multiple pathogenic proteins implicated in neuronopathic Gaucher disease mice.

Xu YH et al.
Hum Mol Genet.,  (2014)

publication_link

 

hr_line

Prolonged myelination in human neocortical evolution.

WB / Human, Chimpanzee

Miller DJ et al.
Proc Natl Acad Sci U S A.,  (2012)

publication_link

 

hr_line

Neuro-glial and systemic mechanisms of pathological responses in rat models of primary blast overpressure compared to composite blast.

IHC-P / Rat

Svetlov SI et al.
Front Neurol.,  (2012)

publication_link

 

hr_line

SIRT2 inhibition achieves neuroprotection by decreasing sterol biosynthesis.

ICC/IF / Mouse

Luthi-Carter R et al.
Proc Natl Acad Sci U S A.,  (2010)

publication_link

 

hr_line

Internalized somatostatin receptor subtype 2 in neuroendocrine tumors of octreotide-treated patients.

ICC/IF, IHC-P / Human

Reubi JC et al.
J Clin Endocrinol Metab.,  (2010)

publication_link

 

hr_line

Axonal prion protein is required for peripheral myelin maintenance.

WB / Mouse

Bremer J et al.
Nat Neurosci.,  (2010)

publication_link

 

hr_line

Protection of neurons from apoptosis by apolipoprotein E-containing lipoproteins does not require lipoprotein uptake and involves activation of phospholipase Cgamma1 and inhibition of calcineurin.

ICC/IF / Mouse, Rat

Hayashi H et al.
J Biol Chem.,  (2009)

publication_link

 

hr_line

miR-23 regulation of lamin B1 is crucial for oligodendrocyte development and myelination.

WB, ICC/IF, IHC-FoFr / Mouse

Lin ST et al.
Dis Model Mech.,  (2009)

publication_link

 

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