anti-Collagen IX antibody

Key features and details

  • 产品描述: Rabbit Polyclonal antibody recognizes Collagen IX
  • 反应物种: Hu, Ms, Rat, Bov
  • 应用: ELISA, FACS, ICC/IF, IHC, IP, WB
  • 特异性: The antibody reacts with collagen type IX from Human, Mouse, Rat and Bovine. It exhibits no cross reactivity.
  • 宿主: Rabbit
  • 克隆: Polyclonal
  • 同位型: IgG
  • 靶点名称: Collagen IX
  • 抗原物种: Rat
  • Brand:
CAT.NO. : ARG23685
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Product Details
概述
产品描述Rabbit Polyclonal antibody recognizes Collagen IX
反应物种Hu, Ms, Rat, Bov
应用ELISA, FACS, ICC/IF, IHC, IP, WB
特异性The antibody reacts with collagen type IX from Human, Mouse, Rat and Bovine. It exhibits no cross reactivity.
宿主Rabbit
克隆Polyclonal
同位型IgG
靶点名称Collagen IX
抗原物种Rat
抗原Collagen type IX from Rat chondrosarcoma.
偶联标记Un-conjugated
別名MED; EDM6; STL4; DJ149L1.1.2; Collagen alpha-1(IX) chain
应用说明
应用建议
应用推荐稀释比
ELISAAssay-dependent
FACSAssay-dependent
ICC/IFAssay-dependent
IHC5 - 15 µg/ml
IP10 - 30 µg/ml
WB300 - 1200 ng/ml
应用说明* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
属性
形式Liquid
纯化Purified by affinity chromatography.
缓冲液PBS
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
数据库连接

GeneID: 12839 Mouse COL9A1

GeneID: 1297 Human COL9A1

Swiss-port # P20849 Human Collagen alpha-1(IX) chain

Swiss-port # Q05722 Mouse Collagen alpha-1(IX) chain

基因名称COL9A1
全名collagen, type IX, alpha 1
背景介绍This gene encodes one of the three alpha chains of type IX collagen, which is a minor (5-20%) collagen component of hyaline cartilage. Type IX collagen is usually found in tissues containing type II collagen, a fibrillar collagen. Studies in knockout mice have shown that synthesis of the alpha 1 chain is essential for assembly of type IX collagen molecules, a heterotrimeric molecule, and that lack of type IX collagen is associated with early onset osteoarthritis. Mutations in this gene are associated with osteoarthritis in humans, with multiple epiphyseal dysplasia, 6, a form of chondrodysplasia, and with Stickler syndrome, a disease characterized by ophthalmic, orofacial, articular, and auditory defects. Two transcript variants that encode different isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]
生物功能Structural component of hyaline cartilage and vitreous of the eye. [UniProt]
预测分子量92 kDa
翻译后修饰Covalently linked to the telopeptides of type II collagen by lysine-derived cross-links.

Prolines at the third position of the tripeptide repeating unit (G-X-Y) are hydroxylated in some or all of the chains. [UniProt]
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