anti-COX1 antibody
Key features and details
- 产品描述:
- 反应物种:
- 应用:
- 特异性:
- 宿主:
- 克隆:
- 同位型:
- 靶点名称:
- 抗原物种:
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Brand:
Product Details
| 产品描述 | Goat Polyclonal antibody recognizes COX1 |
|---|---|
| 反应物种 | Hu, Ms |
| 应用 | ICC/IF, WB |
| 特异性 | This antibody is expected to recognise both human isoforms of this protein according to NP_000953.2 and NP_542158.1. |
| 宿主 | Goat |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | COX1 |
| 抗原物种 | Human |
| 抗原 | C-QDDGPAVERPSTEL |
| 偶联标记 | Un-conjugated |
| 別名 | Prostaglandin H2 synthase 1; COX-1; PHS1; Cyclooxygenase-1; PGHS1; COX3; COX1; PGG/HS; PTGHS; PES-1; EC 1.14.99.1; PHS 1; Prostaglandin-endoperoxide synthase 1; PGHS-1; PCOX1; PGH synthase 1; Prostaglandin G/H synthase 1 |
| 应用建议 |
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|---|---|---|---|---|---|---|---|
| 应用说明 | WB: Recommend incubate at RT for 1h. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
| 形式 | Liquid |
|---|---|
| 纯化 | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| 缓冲液 | Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 0.5% BSA |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
| 数据库连接 | |
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| 背景介绍 | Prostaglandin-endoperoxide synthase (PTGS), also known as cyclooxygenase, is the key enzyme in prostaglandin biosynthesis, and acts both as a dioxygenase and as a peroxidase. There are two isozymes of PTGS: a constitutive PTGS1 and an inducible PTGS2, which differ in their regulation of expression and tissue distribution. This gene encodes PTGS1, which regulates angiogenesis in endothelial cells, and is inhibited by nonsteroidal anti-inflammatory drugs such as aspirin. PTGS1 is thought to be involved in cell-cell signaling and maintaining tissue homeostasis. Alternative splicing of this gene generates two transcript variants. The expression of these two transcripts is differentially regulated by relevant cytokines and growth factors. [provided by RefSeq, Jul 2008] |
| 研究领域 | Cancer antibody; Cell Biology and Cellular Response antibody; Immune System antibody; Metabolism antibody; Signaling Transduction antibody |
| 预测分子量 | 69 kDa |
ARG63193 anti-COX1 antibody WB image
Western blot: HeLa lysate (RIPA buffer, 30µg total protein per lane) stained with ARG63193 anti-COX1 antibody at 1 µg/ml dilution.
ARG63193 anti-COX1 antibody ICC/IF image
Immunofluorescence: Paraformaldehyde fixed NIH/3T3 cells permeabilized with 0.15% Triton. Cells were stained with ARG63193 anti-COX1 antibody (green) at 5 µg/ml dilution for 1 hour. DAPI (blue) for nuclear staining. Negative control: Unimmunized goat IgG (green) at 5 µg/ml dilution.
ARG63193 anti-COX1 antibody WB image
Western blot: 35 µg of U937 cell lysate (in RIPA buffer) stained with ARG63193 anti-COX1 antibody at 2 µg/ml dilution and incubated at RT for 1 hour.
ARG63193 anti-COX1 antibody WB image
Western blot: 35 µg of Mouse kidney (A) and skeletal muscle (B) lysates (in RIPA buffer) stained with ARG63193 anti-COX1 antibody at 0.5 µg/ml dilution and incubated at RT for 1 hour.
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