anti-COX4 antibody

Key features and details

  • 产品描述: Rabbit Polyclonal antibody recognizes COX4
  • 反应物种: Hu, Ms, Rat
  • 应用: ICC/IF, IHC-P, IP, WB
  • 宿主: Rabbit
  • 克隆: Polyclonal
  • 同位型: IgG
  • 靶点名称: COX4
  • 抗原物种: Human
  • 抗原: Recombinant protein of Human COX IV (NP_001852.1)
  • Brand:
CAT.NO. : ARG55304
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Product Details
概述
产品描述Rabbit Polyclonal antibody recognizes COX4
反应物种Hu, Ms, Rat
应用ICC/IF, IHC-P, IP, WB
宿主Rabbit
克隆Polyclonal
同位型IgG
靶点名称COX4
抗原物种Human
抗原Recombinant protein of Human COX IV (NP_001852.1)
偶联标记Un-conjugated
別名Cytochrome c oxidase polypeptide IV; COX4; COX4-1; COXIV; Cytochrome c oxidase subunit IV isoform 1; COX IV-1; Cytochrome c oxidase subunit 4 isoform 1, mitochondrial; COX4I1
应用说明
应用建议
应用推荐稀释比
ICC/IF1:50 - 1:200
IHC-P1:50 - 1:200
IP1:50 - 1:200
WB1:500 - 1:2000
应用说明* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
阳性对照Mouse kidney and HepG2
属性
形式Liquid
纯化Affinity purification with immunogen.
缓冲液PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol
抗菌剂0.02% Sodium azide
稳定剂50% Glycerol
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
数据库连接

GeneID: 12857 Mouse COX4I1

GeneID: 1327 Human COX4I1

GeneID: 29445 Rat COX4I1

基因名称COX4I1
全名cytochrome c oxidase subunit IV isoform 1
背景介绍Cytochrome c oxidase (COX) is the terminal enzyme of the mitochondrial respiratory chain. It is a multi-subunit enzyme complex that couples the transfer of electrons from cytochrome c to molecular oxygen and contributes to a proton electrochemical gradient across the inner mitochondrial membrane. The complex consists of 13 mitochondrial- and nuclear-encoded subunits. The mitochondrially-encoded subunits perform the electron transfer and proton pumping activities. The functions of the nuclear-encoded subunits are unknown but they may play a role in the regulation and assembly of the complex. This gene encodes the nuclear-encoded subunit IV isoform 1 of the human mitochondrial respiratory chain enzyme. It is located at the 3' of the NOC4 (neighbor of COX4) gene in a head-to-head orientation, and shares a promoter with it. Pseudogenes related to this gene are located on chromosomes 13 and 14. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jan 2016]
生物功能COX4 protein is one of the nuclear-coded polypeptide chains of cytochrome c oxidase, the terminal oxidase in mitochondrial electron transport. [UniProt]
研究领域Cancer antibody; Controls and Markers antibody; Metabolism antibody; Signaling Transduction antibody; Loading Control antibody for Cytoplasmic Fractions; Cytochrome-C fractionation Study antibody; Mitochondrial Marker antibody
预测分子量20 kDa
检测图片 (2)
  • ARG55304 anti-COX4 antibody ICC/IF image

    Immunofluorescence: HeLa cells stained with ARG55304 anti-COX4 antibody.

  • ARG55304 anti-COX4 antibody WB image

    Western blot: Mouse kidney and HepG2 cell lysates stained with ARG55304 anti-COX4 antibody.

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