anti-CPI-17 phospho (Thr38) antibody
Key features and details
- 产品描述:
- 反应物种:
- 预测物种:
- 应用:
- 宿主:
- 克隆:
- 同位型:
- 靶点名称:
- 抗原物种:
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Brand:
CAT.NO. : ARG66692
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Product Details
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes CPI-17 phospho (Thr38) |
|---|---|
| 反应物种 | Hu, Ms |
| 预测物种 | Rat |
| 应用 | IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | CPI-17 |
| 抗原物种 | Human |
| 抗原 | Phosphospecific peptide around Thr38 of Human CPI-17. |
| 偶联标记 | Un-conjugated |
| 別名 | CPI-17; Protein kinase C-potentiated inhibitor protein of 17 kDa; CPI17; 17 kDa PKC-potentiated inhibitory protein of PP1; PPP1INL; Protein phosphatase 1 regulatory subunit 14A |
应用说明
| 应用建议 |
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|---|---|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| 阳性对照 | RAW264.7 | ||||||
| 实际分子量 | ~ 20 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purification with immunogen. |
| 缓冲液 | PBS, 0.02% Sodium azide, 50% Glycerol and 0.5% BSA. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 50% Glycerol and 0.5% BSA |
| 浓度 | 1 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | Swiss-port # Q91VC7 Mouse Protein phosphatase 1 regulatory subunit 14A Swiss-port # Q96A00 Human Protein phosphatase 1 regulatory subunit 14A |
|---|---|
| 基因名称 | PPP1R14A |
| 全名 | protein phosphatase 1, regulatory (inhibitor) subunit 14A |
| 背景介绍 | The protein encoded by this gene belongs to the protein phosphatase 1 (PP1) inhibitor family. This protein is an inhibitor of smooth muscle myosin phosphatase, and has higher inhibitory activity when phosphorylated. Inhibition of myosin phosphatase leads to increased myosin phosphorylation and enhanced smooth muscle contraction. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq, Sep 2011] |
| 生物功能 | Inhibitor of PPP1CA. Has over 1000-fold higher inhibitory activity when phosphorylated, creating a molecular switch for regulating the phosphorylation status of PPP1CA substrates and smooth muscle contraction. [UniProt] |
| 细胞定位 | Cytoplasm. [UniProt] |
| 预测分子量 | 17 kDa |
检测图片 (2)
ARG66692 anti-CPI-17 phospho (Thr38) antibody IHC-P image
Immunohistochemistry: Paraffin-embedded Human breast carcinoma tissue stained with ARG66692 anti-CPI-17 phospho (Thr38) antibody. The picture on the right is blocked with the phosphopeptide.
ARG66692 anti-CPI-17 phospho (Thr38) antibody WB image
Western blot: RAW264.7 cell lysates stained with ARG66692 anti-CPI-17 phospho (Thr38) antibody. The lane on the right is blocked with the phosphopeptide.
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