anti-CPI17 antibody [4H10]

CAT.NO. : ARG56957

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Size:

50 μl

*产品价格可能会有所调整，请以品牌方官网实时更新的价格为准，以确保准确性。

Product Details

概述

产品描述	Mouse Monoclonal antibody [4H10] recognizes CPI17
反应物种	Hu
应用	ICC/IF, WB
宿主	Mouse
克隆	Monoclonal
克隆号	4H10
同位型	IgG2a, kappa
靶点名称	CPI17
抗原物种	Human
抗原	Recombinant fragment around aa. 1-147 of Human CPI-17.
偶联标记	Un-conjugated
別名	CPI-17; Protein kinase C-potentiated inhibitor protein of 17 kDa; CPI17; 17 kDa PKC-potentiated inhibitory protein of PP1; PPP1INL; Protein phosphatase 1 regulatory subunit 14A

应用说明

应用建议

应用	推荐稀释比
ICC/IF	Assay-dependent
WB	1:500 - 1:1000

应用说明

* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

属性

形式	Liquid
纯化	Purification with Protein G.
缓冲液	PBS (pH 7.4), 0.02% Sodium azide and 10% Glycerol.
抗菌剂	0.02% Sodium azide
稳定剂	10% Glycerol
浓度	1 mg/ml
存放说明	For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项	For laboratory research only, not for drug, diagnostic or other use.

生物信息

数据库连接	GeneID: 94274 Human PPP1R14A Swiss-port # Q96A00 Human Protein phosphatase 1 regulatory subunit 14A
基因名称	PPP1R14A
全名	protein phosphatase 1, regulatory (inhibitor) subunit 14A
背景介绍	The protein encoded by this gene belongs to the protein phosphatase 1 (PP1) inhibitor family. This protein is an inhibitor of smooth muscle myosin phosphatase, and has higher inhibitory activity when phosphorylated. Inhibition of myosin phosphatase leads to increased myosin phosphorylation and enhanced smooth muscle contraction. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq, Sep 2011]
生物功能	Inhibitor of PPP1CA. Has over 1000-fold higher inhibitory activity when phosphorylated, creating a molecular switch for regulating the phosphorylation status of PPP1CA substrates and smooth muscle contraction. [UniProt]
预测分子量	17 kDa

检测图片 (2)

ARG56957 anti-CPI17 antibody [4H10] ICC/IF image
Immunoflorescense: A549 cell line stained with ARG56957 anti-CPI17 antibody [4H10] at 1:100 (Green).
DAPI (Blue) for nucleus staining.
ARG56957 anti-CPI17 antibody [4H10] WB image
Western blot: 40 µg of 1) A549 cell lysate, 2) NIH-3T3 cell lysate stained with ARG56957 anti-CPI17 antibody [4H10] at 1:500.

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