anti-CPOX antibody [36B10]
![anti-CPOX antibody [36B10]](/upload/image/products/ARG57069_WB_1_210_205.jpg)
![anti-CPOX antibody [36B10]](/upload/image/products/ARG57069_WB_1.jpg)
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CAT.NO. : ARG57069
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Product Details
概述
| 产品描述 | Mouse Monoclonal antibody [36B10] recognizes CPOX |
|---|---|
| 反应物种 | Hu |
| 应用 | WB |
| 宿主 | Mouse |
| 克隆 | Monoclonal |
| 克隆号 | 36B10 |
| 同位型 | IgG1, kappa |
| 靶点名称 | CPOX |
| 抗原物种 | Human |
| 抗原 | Recombinant fragment around aa. 111-454 of Human CPOX. |
| 偶联标记 | Un-conjugated |
| 別名 | HCP; CPO; COX; Coproporphyrinogenase; Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial; CPX; Coprogen oxidase; EC 1.3.3.3 |
应用说明
| 应用建议 |
| ||||
|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purification with Protein A. |
| 缓冲液 | PBS (pH 7.4), 0.02% Sodium azide and 10% Glycerol. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 10% Glycerol |
| 浓度 | 1 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | Swiss-port # P36551 Human Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial |
|---|---|
| 基因名称 | CPOX |
| 全名 | coproporphyrinogen oxidase |
| 背景介绍 | The protein encoded by this gene is the sixth enzyme of the heme biosynthetic pathway. The encoded enzyme is soluble and found in the intermembrane space of mitochondria. This enzyme catalyzes the stepwise oxidative decarboxylation of coproporphyrinogen III to protoporphyrinogen IX, a precursor of heme. Defects in this gene are a cause of hereditary coproporphyria (HCP).[provided by RefSeq, Oct 2009] |
| 生物功能 | Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX. [UniProt] |
| 预测分子量 | 50 kDa |
检测图片 (1)
ARG57069 anti-CPOX antibody [36B10] WB image
Western blot: 40 µg of 1) Recombinant protein CPOX, 2) 293T cell lysate, 3) HepG2 cell lysate, 4) A549 cell lysate, 5) Jurkat cell lysate, 6) K562 cell lysate, 7) LnCaP cell lysate stained with ARG57069 anti-CPOX antibody [36B10] at 1:500.
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